A gene involved in the development of spinal muscular atrophy (SMA) has been found on
human chromosome 5 after a 4-year search. Named the neuronal apoptosis inhibitor protein …

The spinal muscular atrophies (SMAs), characterized by spinal cord motor neuron depletion,
are among the most common autosomal recessive disorders. One model of SMA …

Two genes are known to be involved in spinal muscular atrophy (SMA), namely, SMN
(survival motor neuron) and NAIP (neuronal apoptosis inhibitory protein). Deletion analysis …

The spinal muscular atrophies (SMA), characterized by motor neuron loss and progressive
paralysis, are among the most common autosomal recessive disorders. Recently, two SMA …

The molecular genetic diagnosis of spinal muscular atrophy (SMA) has recently been
complicated by the identification of two candidate genes, which are often deleted in affected …

Spinal muscular atrophy (SMA) is an autosomal recessive disorder characterized by
degeneration of lower motor neurons. We have assayed deletions in two candidate genes …

Two genes, ie survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP)
have been mapped to the SMA region of chromosome 5q13. Both genes are frequently …

Most patients with spinal muscular atrophy (SMA) have been reported to show homozygous
deletion of the gene responsible for SMA, SMN1. However, whether SMA patients with …

Almost to the century after the initial clinical description of childhood spinal muscular atrophy
(SMA)(Werdnig, 1891) a new era of investigation into the nature of SMA was inaugurated …

We have assayed deletions of two candidate genes for spinal muscular atrophy (SMA), the
survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes, in 101 …