Canadian atrial fibrillation anticoagulation study: were the patients subsequently treated with warfarin? Canadian Atrial Fibrillation Anticoagulation Study Group.

A Laupacis, K Sullivan - CMAJ: Canadian Medical Association …, 1996 - ncbi.nlm.nih.gov
OBJECTIVE: To determine the effect of the results of clinical trials on the behaviour of
patients and physicians, the authors ascertained the proportion of patients participating in …

Lessons from warfarin trials in atrial fibrillation: Missing the window of opportunity

CH Tegeler, CD Furberg - Data Monitoring in Clinical Trials: A Case …, 2006 - Springer
Abstract Between September 1985 and June 1987, five clinical trials were initiated to
evaluate the use of warfarin to prevent stroke in patients with nonrheumatic, non-valvular …

Canadian atrial fibrillation anticoaguiation (CAFA) study

SJ Connolly, A Laupacis, M Gent, RS Roberts… - Journal of the American …, 1991 - Elsevier
Abstract The Canadian Atrial Fibrillation Anticoagulation Study was a randomized double-
blind placebo-controlled trial to assess the potential of warfarin to reduce systemic …

The influence of randomized trials on the use of anticoagulants for atrial fibrillation.

GE Mead, JM Wardlaw, SC Lewis, M McDowall… - Age and …, 1999 - academic.oup.com
INTRODUCTION: Anticoagulants and anti-platelet drugs have been shown in randomized
trials to reduce the risk of stroke in patients with atrial fibrillation (AF). We therefore …

Use of warfarin in non-rheumatic atrial fibrillation: a commentary from general practice.

KG Sweeney, DP Gray, R Steele, P Evans - British Journal of General …, 1995 - bjgp.org
Seven randomized trials published in the last six years have shown that warfarin reduces
the risk of ischaemic strokes and death in patients with atrial fibrillation. The annual rates of …

Anticoagulant prophylaxis against stroke in atrial fibrillation: effectiveness in actual practice

JJ Caro, KM Flegel, ME Orejuela, HE Kelley… - CMAJ, 1999 - Can Med Assoc
Background: Randomized trials have shown a beneficial effect of anticoagulation with
warfarin to prevent stroke in atrial fibrillation. It is not known whether the same effect will be …

[PDF][PDF] Warfarin to prevent thromboembolism in chronic atrial fibrillation

FWA Verheugt, TW Galema, TO Cheng, P Petersen… - The Lancet, 1989 - academia.edu
thromboembolic complications less often in their warfarin-treated group (1-5%) than in the
placebo group (6-2%) the conclusion that" it seems reasonable to recommend …

Risks of long-term oral anticoagulation in a non-trial medical environment.

CJ McKenna, J Galvin, HA McCann… - Irish Medical …, 1996 - europepmc.org
Randomised controlled trials have shown that anticoagulation with warfarin reduces the risk
of stroke in patients with atrial fibrillation by two thirds. However there is concern as to …

Anticoagulation therapy for stroke prevention in atrial fibrillation: how well do randomized trials translate into clinical practice?

AS Go, EM Hylek, Y Chang, KA Phillips, LE Henault… - Jama, 2003 - jamanetwork.com
ContextWarfarin has been shown to be highly efficacious for preventing thromboembolism in
atrial fibrillation in randomized trials, but its effectiveness and safety in clinical practice is …

Additional risk factors in atrial fibrillation patients not receiving warfarin.

S Wensley, S Keir, S Caine, M Mac Mahon - Age and ageing, 1999 - academic.oup.com
OBJECTIVE: To study how many elderly inpatients with previously diagnosed atrial
fibrillation were not receiving anticoagulant prophylaxis, and the prevalence of additional …