Histamine H2-receptor antagonists and proton pump inhibitors are the main classes of drug
used to inhibit gastric acid secretion. The former act by reversibly blocking the action of …

Old drug new indication: Antihistamine for the pain in your stomach? Page 1 Australian
Pharmacist June 2016 i ©Pharmaceutical Society of Australia Ltd. 32 FEATURE Antihistamine …

Antihistamines comprise a broad class of medicines that include the first-generation,
centrally-acting, H1-receptor antagonists (eg chlorpheniramine, diphenhydramine) and the …

Abstract H2-receptor antagonists (fagamet [cimetidine], Zantac [ranitidine], Pepcid
[famotidine], Axid [nizatidine]) decrease the volume and concentration of gastric acid …

Clinical Perspectives of Drugs Inhibiting Acid Secretion: Histamine H₂
Antagonists Page 1 Clinical Perspectives of Drugs Inhibiting Acid Secretion: Histamine H2 …

Histamine is one of the most extensively studied biological amines in medicine. It stimulates
smooth muscle contraction and gastric acid secretion, increases vascular permeability …

Editor's note. From time to time, Gastroenterology publishes articles designed to summarize
the evidence for a particular point of view concerning some fundamental aspect of …

Anti-secretory drugs (also known as acid suppressants) are drugs that inhibit parietal cell
HCl secretion. They differ from antacids (eg, aluminum and magnesium hydroxide), which …

The marketing of cimetidine in the United Kingdom in November, 1976, and in the United
States in August, 1977, was the culmination of a research and development program that …