Bench to Bedside

Canadian Medical Association - CMAJ, 2006 - Can Med Assoc
St. John's Wort, a widely used herbal remedy for depression, has been recently shown to
contain a component that inhibits HIV replication. Although the findings are preliminary and …

p27SJ, a novel protein in St John's Wort, that suppresses expression of HIV-1 genome

N Darbinian-Sarkissian, A Darbinyan, J Otte… - Gene therapy, 2006 - nature.com
Transcription of the HIV-1 genome is controlled by the cooperation of viral regulatory
proteins and several host factors which bind to specific DNA sequences within the viral …

Creation of a bi-directional protein transduction system for suppression of HIV-1 expression by p27SJ

N Darbinian, Y Popov, K Khalili, S Amini - Antiviral research, 2008 - Elsevier
p27SJ is a novel protein from a callus culture of St. John's wort whose expression modulates
transcription of the HIV-1 promoter in several mammalian cells [Darbinian-Sarkissian, N …

[CITATION][C] Potential HIV treatment that targets host-cell pathway

K Muthumani - Inpharma, 2004 - Springer
RWJ 67657, a selective inhibitor of the serinethreonine protein kinase p38, inhibits viral
replication in HIV-infected cells, report researchers from the US.* First, the researchers …

St. John's wort and schizophrenia

S Lal, H Iskandar - CMAJ, 2000 - Can Med Assoc
In recent years St. John's wort has become a popular natural medicine for the treatment of
depression1 and general symptoms such as tiredness and lack of energy. Unfortunately, the …

[PDF][PDF] St. John's wort and schizophrenia

JB Hunter - Citeseer
In recent years St. John's wort has become a popular natural medicine for the treatment of
depression1 and general symptoms such as tiredness and lack of energy. Unfortunately, the …

HIV infection and AIDS

LM Bedoya, N Marquez, N Martinez… - Infection, 2009 - journals.lww.com
Bedoya LM, Marquez N, Martinez N, Gutierrez-Eisman S, et al. SJ23B, a jatrophane
diterpene activates classical PKCs and displays strong activity against HIV in vitro. Biochem …

[HTML][HTML] Naturally occurring compounds elicit HIV-1 replication in chronically infected promonocytic cells

AA Barquero, ME Dávola, DA Riva… - BioMed research …, 2014 - hindawi.com
Since antiretroviral therapy suppresses but does not eradicate HIV-1 infection, methods to
purge viral reservoirs are required. Many strategies involve the reactivation of chronically …

[PDF][PDF] Phytochemicals may arrest HIV-1 progression B. Sharma

CACAC AIDSANDPREVENTION - academia.edu
The application of current antiretroviral chemotherapeutics such as antiHIV-1 RT drugs
(nucleoside, nucleotide and non-nucleotide reverse transcriptase inhibitors) as well as …

[PDF][PDF] Research Article Naturally Occurring Compounds Elicit HIV-1 Replication in Chronically Infected Promonocytic Cells

AA Barquero, ME Dávola, DA Riva, SE Mersich… - academia.edu
Since antiretroviral therapy suppresses but does not eradicate HIV-1 infection, methods to
purge viral reservoirs are required. Many strategies involve the reactivation of chronically …