An entirely safe and reliable anticoagulant for the prophylaxis or treatment of thrombo-
embolism has yet to be discovered, but recently an entirely new approach to the prob-lem …

Abstract'Arvin', the purified active fraction of the venom of Agkistrodon rhodostoma, the
Malayan pit-viper, produced controlled defibrination in nine patients in whom anticoagulant …

In some units where this policy has been adopted the incidence of alarming side-effects has
been so high that it has been abandoned. It would be interesting to know whether in these …

England. Many commercial extracts, in fact, are quite insensitive to factor vn, which may be
the only factor reduced in the first 48 hours of treatment. The term ratio is preferred by some …

Anticoagulant therapy has been carried out by producing defibrination in nineteen patients
by means of a purified coagulant fraction ('Arvin') derived from the venom of the Malayan pit …

Because of dissatisfaction with control of anticoagulant therapy by means of the simple one-
stage prothronbin method, the authors developed a modified“prothrombin and proconvertin” …

THROMBOSIS of the deep veins of the lower limbs is a hazard common to obstetric,
medical, surgical, and traumatic cases, and its embolic complication is the dread of …

METHOD When venous thrombosis has been diagnosed, the labora-tory is in-formed, and
treatment is started imme-diately with anticoagu-lants accord-ing to the following plan: First …

(2) The treated and control groups should have an equal distribution of factors known to
have an unfavourable influence on prognosis. The data given show that in the first week of …

Systemic poisoning resulting from a bite by the Malayan pit viper (Agkistrodon rhodostoma)
always results in non-clotting blood but spontaneous bleeding is trivial, and neurotoxic …