Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence

S Rahman, MTV Montero, K Rowe… - Expert review of …, 2021 - Taylor & Francis
Introduction The COVID-19 pandemic has created a public health crisis, infected millions of
people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to …

[HTML][HTML] The role and therapeutic potential of NF-kappa-B pathway in severe COVID-19 patients

A Hariharan, AR Hakeem, S Radhakrishnan… - …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) pandemic has affected health care systems
worldwide. Severe presentations of COVID-19 such as severe pneumonia and acute …

Effect of hydrocortisone on mortality and organ support in patients with severe COVID-19: the REMAP-CAP COVID-19 corticosteroid domain randomized clinical trial

DC Angus, L Derde, F Al-Beidh, D Annane, Y Arabi… - Jama, 2020 - jamanetwork.com
Importance Evidence regarding corticosteroid use for severe coronavirus disease 2019
(COVID-19) is limited. Objective To determine whether hydrocortisone improves outcome for …

[PDF][PDF] Therapeutics and COVID-19: living guideline, 16 September 2022

World Health Organization - 2022 - apps.who.int
As of August 2022, there have been over 572 million confirmed cases of COVID-19 (9). The
pandemic has thus far claimed approximately 6.39 million lives (9). Vaccination is having a …

A living WHO guideline on drugs for covid-19

A Agarwal, BJ Hunt, M Stegemann, B Rochwerg… - bmj, 2020 - bmj.com
Updates This is the fourteenth version (thirteenth update) of the living guideline, replacing
earlier versions (available as data supplements). New recommendations will be published …

Vitamin D and survival in COVID-19 patients: A quasi-experimental study

C Annweiler, B Hanotte, CG de l'Eprevier… - The Journal of steroid …, 2020 - Elsevier
Vitamin D may be a central biological determinant of COVID-19 outcomes. The objective of
this quasi-experimental study was to determine whether bolus vitamin D3 supplementation …

[HTML][HTML] Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis

D Chaudhuri, K Sasaki, A Karkar, S Sharif… - Intensive care …, 2021 - Springer
Purpose Corticosteroids are now recommended for patients with severe COVID-19 including
those with COVID-related ARDS. This has generated renewed interest regarding whether …

Impact of corticosteroids in coronavirus disease 2019 outcomes: systematic review and meta-analysis

EJ Cano, XF Fuentes, CC Campioli, JC O'Horo… - Chest, 2021 - Elsevier
Background Since its appearance in late 2019, infections caused by severe acute
respiratory syndrome coronavirus 2 have created unprecedented challenges for health …

[HTML][HTML] COVID-19: Advances in diagnostic tools, treatment strategies, and vaccine development

M Sreepadmanabh, AK Sahu, A Chande - Journal of biosciences, 2020 - Springer
An unprecedented worldwide spread of the SARS-CoV-2 has imposed severe challenges
on healthcare facilities and medical infrastructure. The global research community faces …

Corticosteroids in COVID-19 ARDS: evidence and hope during the pandemic

HC Prescott, TW Rice - Jama, 2020 - jamanetwork.com
Corticosteroids, such as hydrocortisone and dexamethasone, haveanti-inflammatory,
antifibrotic, andvasoconstrictiveeffects, which intensivists have been trying to leverage for …