Abstract Objectives Discrete choice experiments (DCEs) are increasingly advocated as a
way to quantify preferences for health. However, increasing support does not necessarily …

Conjoint analysis is a stated-preference survey method that can be used to elicit responses
that reveal preferences, priorities, and the relative importance of individual features …

This paper summarizes the current controversies surrounding the identification and
disclosure of “incidental” or “secondary” findings from genomic sequencing and the …

Purpose: Implementation of novel genetic diagnostic tests is generally driven by
technological advances because they promise shorter turnaround times and/or higher …

The Clinical Sequencing Evidence-Generating Research (CSER) consortium, now in its
second funding cycle, is investigating the effectiveness of integrating genomic (exome or …

Despite rapid technical progress and demonstrable effectiveness for some types of
diagnosis and therapy, much remains to be learned about clinical genome and exome …

Genomic testing is becoming routine for diagnosing rare childhood genetic disease.
Evidence underlying sustainable implementation is limited, focusing on short-term endpoints …

Purpose To estimate the personal utility and uptake of genomic sequencing (GS) across
pediatric and adult-onset genetic conditions. Methods Three discrete choice experiment …

Background Next-generation sequencing (NGS) technologies have seen variable adoption
in the clinic. This is partly due to a lack of clinical and economic studies, with the latter …

Background A key ethical question in genomics research relates to whether individual
genetic research results should be disclosed to research participants and if so, which results …