[HTML][HTML] Safety profile of COVID-19 drugs in a real clinical setting

MN Chiu, M Bhardwaj, SP Sah - European Journal of Clinical …, 2022 - Springer
Purpose The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus has affected millions all over the world and has …

[HTML][HTML] Bradyarrhythmia after remdesivir administration in SARS-CoV-2: a review of literature and meta-analysis of observational studies in epidemiology

S Al-Jammali, R Al-Zakhari, N Sheets… - Cardiology …, 2022 - ncbi.nlm.nih.gov
Background The coronavirus disease 2019 (COVID-19) pandemic has required timely and
informed decisions about treatment recommendations for clinical practice. One such drug …

[HTML][HTML] NVX-CoV2373 vaccine efficacy against hospitalization: A post hoc analysis of the PREVENT-19 phase 3, randomized, placebo-controlled trial

AM Marchese, X Zhou, J Kinol, E Underwood, W Woo… - Vaccine, 2023 - Elsevier
Abstract PREVENT-19, the pivotal phase 3 trial of the Novavax adjuvanted, recombinant
spike protein COVID-19 vaccine (NVX-CoV2373), demonstrated that the vaccine was well …

[HTML][HTML] Activation of the urotensin-II receptor by remdesivir induces cardiomyocyte dysfunction

A Ogawa, S Ohira, Y Kato, T Ikuta, S Yanagida… - Communications …, 2023 - nature.com
Remdesivir is an antiviral drug used for COVID-19 treatment worldwide. Cardiovascular side
effects have been associated with remdesivir; however, the underlying molecular …

Remdesivir-associated bradycardia

PR Ching, C Lee - BMJ Case Reports CP, 2021 - casereports.bmj.com
Remdesivir is an antiviral used for the treatment of COVID-19 requiring hospitalisation.
Information on its cardiovascular safety profile is scarce. We report the case of a 37-year-old …

[HTML][HTML] Remdesivir associated sinus bradycardia in patients with COVID-19: A prospective longitudinal study

M Hajimoradi, B Sharif Kashani, F Dastan… - Frontiers in …, 2023 - frontiersin.org
Background: Remdesivir is effective against SARS-Cov-2 with little evidence of its adverse
effect on the cardiac system. The aim of the present study is investigating the incidence of …

Identification of Bradycardia Following Remdesivir Administration Through the US Food and Drug Administration American College of Medical Toxicology COVID-19 …

JM Devgun, R Zhang, J Brent, P Wax… - JAMA Network …, 2023 - jamanetwork.com
Importance The rapid spread and mortality associated with COVID-19 emphasized a need
for surveillance system development to identify adverse events (AEs) to emerging …

[HTML][HTML] Complete AV block in vaccinated COVID-19 patient

K Lee, O Rahimi, N Gupta, C Ahsan - Case Reports in Cardiology, 2022 - hindawi.com
Background. Coronavirus 2019 (COVID-19) was initially identified approximately in
December 2019 at Wuhan, China, as patients presented with vague prodromal and …

[HTML][HTML] Remdesivir-induced bradycardia

SG Kanagala, H Dholiya, P Jhajj, MA Patel… - Southern Medical …, 2023 - ncbi.nlm.nih.gov
Remdesivir, a viral RNA–dependent RNA polymerase inhibitor, found extensive use in
coronavirus disease 2019–infected patients because it curbs the viral load expansion …

[HTML][HTML] Remdesivir-induced bradycardia in patients hospitalized with SARS-CoV2 infection: a possible vagally-mediated mechanism

A Filtz, A Carandina, A Fasiello, L Barbetta… - Internal and Emergency …, 2023 - Springer
Recently, case series studies on patients with SARS-CoV-2 infection reported an
association between remdesivir (RDV) administration and incidental bradycardia. However …