As tranquilizers, benzodiazepines have a wide range of clinical uses. Recently, there has
been a significant rise in the number of novel psychoactive substances, including designer …

The existence of specific binding sites for benzodiazepines (BZs) in the brain has prompted
the search for endogenous BZ receptor ligands designated by the generic term …

The overdose crisis in Canada has continuously evolved and is increasingly challenging to
contain, while efforts from governments and policymakers to address it have often fallen …

In recent years, the number of materials used as drug delivery systems (DDS) has increased
dramatically. The widespread use of DDSs has improved both the safety and efficacy of …

Aromas have a powerful influence in our everyday life and are known to exhibit an array of
pharmacological properties, including anxiolytic, anti-stress, relaxing, and sedative effects …

Objectives: Identify the indications for using diazepam. Summarize the adverse effects of
diazepam. Review the mechanism of action of diazepam. Outline the importance of …

Substance use disorders (SUDs) are a leading cause of death and other ill health effects in
the United States and other countries in the world. Several approaches ranging from …

Introduction Although not a potentially life-threatening poisoning, benzodiazepine (BZD)
intoxication may be life-threatening in special situations/populations or those with …

Gamma-aminobutyric acid (GABA) acts as the principal inhibitory neurotransmitter in the
central nervous system (CNS). Although researchers discovered GABA in biological tissues …

There has been a significant increase in the proportion of opioid samples containing strong
sedatives. These sedatives include benzodiazepines, etizolam, and xylazine. In January …