[HTML][HTML] Missing data is poorly handled and reported in prediction model studies using machine learning: a literature review

SWJ Nijman, AM Leeuwenberg, I Beekers… - Journal of clinical …, 2022 - Elsevier
Objectives Missing data is a common problem during the development, evaluation, and
implementation of prediction models. Although machine learning (ML) methods are often …

[HTML][HTML] When and how should multiple imputation be used for handling missing data in randomised clinical trials–a practical guide with flowcharts

JC Jakobsen, C Gluud, J Wetterslev… - BMC medical research …, 2017 - Springer
Background Missing data may seriously compromise inferences from randomised clinical
trials, especially if missing data are not handled appropriately. The potential bias due to …

[HTML][HTML] Bumetanide for core symptoms of autism spectrum disorder (BAMBI): a single center, double-blinded, participant-randomized, placebo-controlled, phase-2 …

JJ Sprengers, DM Van Andel, NPA Zuithoff… - Journal of the American …, 2021 - Elsevier
Objective Recent trials have indicated positive effects of bumetanide in autism spectrum
disorder (ASD). We tested efficacy of bumetanide on core symptom domains using a single …

The effect of cannabis-based medicine in the treatment of cachexia: a systematic review and meta-analysis

S Hammond, S Erridge, N Mangal… - Cannabis and …, 2021 - liebertpub.com
Background: Cachexia is a prevalent condition associated with underlying chronic disease.
Wasting of skeletal muscle and adipose tissue loss in cachectic patients is associated with …

Efficacy of individual and group hypnotherapy in irritable bowel syndrome (IMAGINE): a multicentre randomised controlled trial

CE Flik, W Laan, NPA Zuithoff, YR van Rood… - The lancet …, 2019 - thelancet.com
Background Hypnotherapy for irritable bowel syndrome (IBS) has been used primarily in
patients with refractory symptoms in specialised departments and delivered on an individual …

Efficacy of regular exercise during pregnancy on the prevention of postpartum depression: the PAMELA randomized clinical trial

CVN Coll, MR Domingues, A Stein… - JAMA network …, 2019 - jamanetwork.com
Importance Interventions to reduce postpartum depression have mainly focused on
enhancing screening to increase treatment rates among women. Preventive approaches are …

[HTML][HTML] Standard whole prostate gland radiotherapy with and without lesion boost in prostate cancer: Toxicity in the FLAME randomized controlled trial

EM Monninkhof, JWL Van Loon, M van Vulpen… - Radiotherapy and …, 2018 - Elsevier
Purpose To compare toxicity rates in patients with localized prostate cancer treated with
standard fractionated external beam radiotherapy (EBRT) with or without an additional …

Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: a pragmatic randomised …

N Hyldig, CA Vinter, M Kruse… - … Journal of Obstetrics …, 2019 - Wiley Online Library
Objective To evaluate the reduction of surgical site infections by prophylactic incisional
negative pressure wound therapy compared with standard postoperative dressings in obese …

Multispecies probiotic for the prevention of antibiotic-associated diarrhea in children: a randomized clinical trial

J Łukasik, T Dierikx, I Besseling-van der Vaart… - JAMA …, 2022 - jamanetwork.com
Importance The efficacy of multispecies probiotic formulations in the prevention of antibiotic-
associated diarrhea (AAD) remains unclear. Objective To assess the effect of a multispecies …

Effects of exergaming on exercise capacity in patients with heart failure: results of an international multicentre randomized controlled trial

T Jaarsma, L Klompstra, T Ben Gal… - European Journal of …, 2021 - Wiley Online Library
Aims Exergaming is a new tool to increase physical activity. This study aimed to determine
the effects of access to a home-based exergame (Nintendo Wii) in patients with heart failure …