BACKGROUND Nanotechnology involves the engineering of structures on a molecular
level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic …

The skin appendages are composed of the eccrine and apocrine sweat glands, the hair
follicles, the sebaceous glands, and the nails (Fig. 1). All of these are embryonically derived …

All forms of life produce nanosized extracellular vesicles called exosomes, which are
enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …

Background: Isotretinoin, a teratogen, is widely used to treat cystic acne. Although the risks
of pregnancy during isotretinoin therapy are well recognized, there are doubts about the …

Background Drug safety is one of the hottest topics in daily medical practice, particularly with
regard to approving new medication or questioning the possibility of withdrawing a drug …

Background. Despite being the first-line treatment for severe or moderate acne, isotretinoin
has several serious side effects that necessitate the evaluation of patients' knowledge about …

Evaluation of human data regarding the outcomes of topical‐retinoid‐exposed pregnancies
is important in terms of counselling pregnant women with inadvertent exposure. The …

Isotretinoin is known as a potent teratogenic agent. Pregnancy should be ruled out before
isotretinoin is prescribed. In this study, we evaluated the fetal outcomes of pregnant women …

Background: Isotretinoin, for treating cystic acne, increases the risk of miscarriage and fetal
abnormalities when taken during pregnancy. The Health Canada–approved product …

Introduction Oral isotretinoin is an effective agent for the treatment of severe cystic acne.
Isotretinoin is a teratogen; there is an increased risk of congenital defects in infants exposed …