The vascular hypothesis of Alzheimer's disease: a key to preclinical prediction of dementia using neuroimaging

J De La Torre - Journal of Alzheimer's Disease, 2018 - content.iospress.com
The vascular hypothesis of Alzheimer's disease (VHAD) was proposed 24 years ago from
observations made in our laboratory using aging rats subjected to chronic brain …

[HTML][HTML] Hypoxia-Induced Neuroinflammation in Alzheimer's Disease: Potential Neuroprotective Effects of Centella asiatica

A Hambali, J Kumar, NFM Hashim, S Maniam… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder that is characterised by the
presence of extracellular beta-amyloid fibrillary plaques and intraneuronal neurofibrillary tau …

[HTML][HTML] Interactions between amyloid-β and hemoglobin: implications for amyloid plaque formation in Alzheimer's disease

JY Chuang, CW Lee, YH Shih, T Yang, L Yu, YM Kuo - PloS one, 2012 - journals.plos.org
Accumulation of amyloid-β (Aβ) peptides in the brain is one of the central pathogenic events
in Alzheimer's disease (AD). However, why and how Aβ aggregates within the brain of AD …

Hypoxia-induced tau phosphorylation and memory deficit in rats

CE Zhang, X Yang, L Li, X Sui, Q Tian, W Wei… - Neurodegenerative …, 2014 - karger.com
Hypoxia was shown to be associated with an increased risk of Alzheimer's disease (AD).
The effects of hypoxia on the development of AD pathology and spatial memory ability and …

[HTML][HTML] The significance of vascular pathogenesis in the examination of corticobasal syndrome

A Dunalska, J Pikul, K Schok, KA Wiejak… - Frontiers in Aging …, 2021 - frontiersin.org
Corticobasal syndrome (CBS) is a clinical entity, classified as an atypical Parkinsonism,
characterized by both motor and higher cortical dysfunctions. The clinical manifestation of …

Rapid evaluation of PHD2 inhibitory activity of natural products based on capillary electrophoresis online stacking strategy

Y Zhang, CY Sang, XR Wang, CB Wang… - … of Chromatography B, 2024 - Elsevier
Abstract Prolyl hydroxylase domain 2 (PHD2) is an important enzyme in the human body
that perceives changes in oxygen concentration and regulates response in hypoxic …

Hypoxia enhances stimulating effect of amyloid beta peptide (25–35) for interleukin 17 and T helper lymphocyte subtype 17 upregulation in cultured peripheral blood …

YH Yin, SR Wen, GZ Li, DS Wang - Microbiology and …, 2009 - Wiley Online Library
Th17 has been demonstrated to have a key role in several autoimmune diseases. The
present study was carried out to investigate changes in IL‐17 and Th17 in cultured PBMC in …

The effects of impaired cerebral circulation on Alzheimer's disease pathology: evidence from animal studies

AE Villarreal, R Barron, KS Rao… - Journal of Alzheimer's …, 2014 - content.iospress.com
Persistent systemic hypoxia, a direct consequence of alterations in vascular function, can
compromise the brain by increasing the risk of developing dementias such as Alzheimer's …

Co-morbidity of depression, anxiety disorders and cognitive function impairment among patients suffering from chronic obstructive pulmonary disease

M Talarowska, A Florkowski, P Gałecki… - … in Dermatology and …, 2009 - termedia.pl
Przewlekła obturacyjna choroba płuc (POChP, chronic obstructive pulmonary disease–
COPD) jest jedną z najczęstszych chorób układu oddechowego, prowadzącą do licznych …

[PDF][PDF] Współwystępowanie zaburzeń depresyjnych, lękowych oraz zaburzeń funkcji poznawczych wśród pacjentów cierpiących na przewlekłą obturacyjną chorobę …

M Talarowska, A Florkowski, P Gałecki… - Postępy Dermatologii i …, 2009 - termedia.pl
Przewlekłe choroby układu oddechowego są poważnym problemem zdrowia publicznego
na świecie. Przewlekła obturacyjna choroba płuc (POChP, chronic obstructive pulmonary …