Chronic kidney disease: global dimension and perspectives

V Jha, G Garcia-Garcia, K Iseki, Z Li, S Naicker… - The Lancet, 2013 - thelancet.com
Chronic kidney disease is defined as a reduced glomerular filtration rate, increased urinary
albumin excretion, or both, and is an increasing public health issue. Prevalence is estimated …

Sex-specific genetic architecture of human disease

C Ober, DA Loisel, Y Gilad - Nature Reviews Genetics, 2008 - nature.com
Sexual dimorphism in anatomical, physiological and behavioural traits are characteristics of
many vertebrate species. In humans, sexual dimorphism is also observed in the prevalence …

Testing, infection and complication rates of COVID-19 among people with a recent history of homelessness in Ontario, Canada: a retrospective cohort study

L Richard, R Booth, J Rayner, KK Clemens… - … Open Access Journal, 2021 - cmajopen.ca
Background: People with a recent history of homelessness are believed to be at high risk of
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and, when …

Association between cardiovascular risk factors and aortic stenosis: the CANHEART aortic stenosis study

AT Yan, M Koh, KK Chan, H Guo, DA Alter… - Journal of the American …, 2017 - jacc.org
Background: Few longitudinal studies have delineated the association between traditional
cardiovascular risk factors and development of aortic stenosis (AS). Objectives: The authors …

Days alive and out of hospital: validation of a patient-centered outcome for perioperative medicine

A Jerath, PC Austin, DN Wijeysundera - Anesthesiology, 2019 - pubs.asahq.org
Abstract Editor's Perspective What We Already Know about This Topic Days alive and out of
hospital is an easily obtained patient-centered outcome What This Article Tells Us That Is …

[HTML][HTML] All-cause mortality and serious cardiovascular events in people with hip and knee osteoarthritis: a population based cohort study

GA Hawker, R Croxford, AS Bierman, PJ Harvey… - PloS one, 2014 - journals.plos.org
Background Because individuals with osteoarthritis (OA) avoid physical activities that
exacerbate symptoms, potentially increasing risk for cardiovascular disease (CVD) and …

Risk of incident diabetes in relation to long-term exposure to fine particulate matter in Ontario, Canada

H Chen, RT Burnett, JC Kwong… - Environmental …, 2013 - ehp.niehs.nih.gov
Background: Laboratory studies suggest that fine particulate matter (≤ 2.5 µm in diameter;
PM2. 5) can activate pathophysiological responses that may induce insulin resistance and …

COVID-19 positivity rates, hospitalizations and mortality of adults with and without intellectual and developmental disabilities in Ontario, Canada

Y Lunsky, A Durbin, R Balogh, E Lin, L Palma… - Disability and health …, 2022 - Elsevier
Background Across and within countries there is a need to understand how the COVID-19
pandemic has impacted populations of individuals with intellectual and developmental …

Changes in the rates of awareness, treatment and control of hypertension in Canada over the past two decades

FA McAlister, K Wilkins, M Joffres, FHH Leenen… - Cmaj, 2011 - Can Med Assoc
Background Analyses of medication databases indicate marked increases in prescribing of
antihypertensive drugs in Canada over the past decade. This study was done to examine …

Residential greenness and cardiovascular disease incidence, readmission, and mortality

H Chen, RT Burnett, L Bai, JC Kwong… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Living in greener areas of cities was linked to increased physical activity levels,
improved mental well-being, and lowered harmful environmental exposures, all of which …