Regenerative medicine and stem cell based drug discovery

K Sakurada, FM McDonald… - Angewandte Chemie …, 2008 - Wiley Online Library
Abstract As William Shakespeare beautifully described, increasing age often causes loss of
tissue and organ function. The increase in average life expectancy in many countries is …

Cloning and Expression of Bioactive Human Granulocyte Colony Stimulating Factor in Pichia Pastoris

SF Chien - Journal of the Chinese Chemical Society, 2010 - Wiley Online Library
For over ten years, recombinant human Granulocyte Colony Stimulating Factor (hG‐CSF)
has been broadly used in clinical applications. Many sources of G‐CSF have the …

Effects of Recombinant Human Granulocyte Colony-Stimulating Factor Filgrastim on ECG Parameters in Neutropenic Patients: A Single-Centre, Prospective Study

O Guneyse, OE Onur, A Denizbasi - Clinical drug investigation, 2009 - Springer
Background and objective: Human granulocyte colony-stimulating factor (G-CSF) is a
haematopoietic hormone that promotes the growth, proliferation, differentiation and …

Regenerative Medizin und stammzellbasierte Wirkstoffentwicklung

K Sakurada, FM McDonald, F Shimada - Angewandte Chemie, 2008 - Wiley Online Library
Abstract Wie es William Shakespeare so eindrucksvoll beschrieb, geht das Altern oft mit
einem Verlust an Gewebe‐und Organfunktionen einher. Mit steigender Lebenserwartung in …

[HTML][HTML] Granulocyte-colony stimulating factor reduces striatal dopamine accumulation caused by cerebral ischemia

HK Liew, CW Hsu, JS Kuo, CY Pang - Tzu Chi Medical Journal, 2012 - Elsevier
OBJECTIVES: Granulocyte-colony stimulating factor (G-CSF) plays important roles in
neuroprotection. Acute and massive increases in extracellular dopamine can cause damage …

Drugs that act on the immune system: cytokines and monoclonal antibodies

FA Goumas, F Braun, DC Broering… - Side effects of Drugs …, 2009 - Elsevier
Publisher Summary This chapter elaborates the different aspects of cytokines and
monoclonal antibodies. Colony-stimulating factors improve granulocyte count in neutropenic …