Neurovascular and cognitive dysfunction in hypertension: epidemiology, pathobiology, and treatment
C Iadecola, RF Gottesman - Circulation research, 2019 - Am Heart Assoc
Hypertension has emerged as a leading cause of age-related cognitive impairment. Long
known to be associated with dementia caused by vascular factors, hypertension has more …
known to be associated with dementia caused by vascular factors, hypertension has more …
[HTML][HTML] Hypertension-induced cognitive impairment: from pathophysiology to public health
Hypertension affects two-thirds of people aged> 60 years and significantly increases the risk
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …
The age-dependent relation of blood pressure to cognitive function and dementia
C Qiu, B Winblad, L Fratiglioni - The Lancet Neurology, 2005 - thelancet.com
The relation of blood pressure with cognitive function and dementia has, in recent years,
received much attention from epidemiological research. Some cross-sectional studies have …
received much attention from epidemiological research. Some cross-sectional studies have …
The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study
F Forette, ML Seux, JA Staessen, L Thijs… - Archives of internal …, 2002 - jamanetwork.com
Background After the double-blind, placebo-controlled Systolic Hypertension in Europe
(Syst-Eur) trial ended in February 1997, randomized patients were offered active study …
(Syst-Eur) trial ended in February 1997, randomized patients were offered active study …
Vascular risk factors, cognitve decline, and dementia
E Duron, O Hanon - Vascular health and risk management, 2008 - Taylor & Francis
Dementia is one of the most important neurological disorders in the elderly. Aging is
associated with a large increase in the prevalence and incidence of degenerative …
associated with a large increase in the prevalence and incidence of degenerative …
Hypertension and the brain: vulnerability of the prefrontal regions and executive functions.
N Raz, KM Rodrigue, JD Acker - Behavioral neuroscience, 2003 - psycnet.apa.org
Untreated hypertension negatively affects brain anatomy and cognitive functions, but the
effects of medically treated hypertension are unclear. The authors compared 40 middle-age …
effects of medically treated hypertension are unclear. The authors compared 40 middle-age …
Solid lipid nanoparticles as vehicles of drugs to the brain: current state of the art
L Gastaldi, L Battaglia, E Peira, D Chirio… - European Journal of …, 2014 - Elsevier
Central nervous system disorders are already prevalent and steadily increasing among
populations worldwide. However, most of the pharmaceuticals present on world markets are …
populations worldwide. However, most of the pharmaceuticals present on world markets are …
Investigation of antihypertensive class, dementia, and cognitive decline: a meta-analysis
Objective High blood pressure is one of the main modifiable risk factors for dementia.
However, there is conflicting evidence regarding the best antihypertensive class for …
However, there is conflicting evidence regarding the best antihypertensive class for …
[HTML][HTML] Intracellular calcium dysregulation: implications for Alzheimer's disease
S Magi, P Castaldo, ML Macrì, M Maiolino… - BioMed research …, 2016 - hindawi.com
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive
neuronal loss. AD is associated with aberrant processing of the amyloid precursor protein …
neuronal loss. AD is associated with aberrant processing of the amyloid precursor protein …
[PDF][PDF] Alzheimer's disease: the pros and cons of pharmaceutical, nutritional, botanical, and stimulatory therapies, with a discussion of treatment strategies from the …
KA Wollen - Altern Med Rev, 2010 - zespoldowna.info
Alzheimer's disease (AD) is characterized by dysfunctional intracellular and extracellular
biochemical processes that result in neuron death. This article summarizes hypotheses …
biochemical processes that result in neuron death. This article summarizes hypotheses …