Case 1: A 36-year-old aboriginal woman has a 12-mm-diameter reaction to a tuberculosis
(TB) skin test, done as part of a community survey. She was vaccinated with BCG (bacille …

Tuberculosis (TB) can be prevented by means of 2 major strategies. The first is to prevent
transmission from patients with active, contagious forms of the disease to uninfected people; …

A series of 5-substituted 2′-deoxyuridine monophosphate analogues has been
synthesized and evaluated as potential inhibitors of mycobacterial ThyX, a novel flavin …

In Mycobacterium tuberculosis (MTB), rifampicin resistance is almost invariably due to
mutations in the rpoB gene, whose function is critical for cell viability. Most of these …

Objectives To compare the hearing of gold miners with and without tuberculosis (TB) to
determine the effect of TB and its associated risk profile on hearing. Methods Audiological …

Eubacterial peptidyl-tRNA hydrolase is an essential enzyme that hydrolyzes peptidyl-tRNAs
that are released into the cytoplasm because of premature termination of translation …

This study describes the formation and properties of a silica nanocolloid drug delivery
system synthesized using micelle formation method. Previously, we have reported feasibility …

Rifabutin is a spiro-piperidyl-rifamycin derived from rifamycin-S. This study was planned to
determine the minimal inhibitory concentrations (MICs) of rifabutin and rifampicin against …

In 2001, the WHO declared TB a global emergency, as one third of the worlds population
suffered from latent M. tuberculosis infection. Today, a decade later, millions of people still …

The tuberculosis (TB) series, which has been running in CMAJ since March 1999, has
already reviewed the changes in populations at risk1 and the emergence of HIV-related2 …