Factor V Leiden is a genetic disorder characterized by a poor anticoagulant response to
activated Protein C and an increased risk for venous thromboembolism. Deep venous …

Congenital causes of venous thrombosis have gained increasing prominence with the
description of the factor V Leiden mutation and the prothrombin gene mutation. More …

Objective To further characterize the clinical and pathologic features, disease associations,
and laboratory abnormalities of livedoid vasculopathy. Design Retrospective study of …

OBJECTIVE: The objective of this study was to determine the changes in activated protein C
resistance that occur during normal pregnancy. STUDY DESIGN: In this cross-sectional …

To determine whether the factor V Leiden mutation is associated with decreased bleeding in
individuals with severe hemophilia A, factor concentrate utilization, maximum annual …

Thrombophilia testing is frequently performed after an ischemic stroke, particularly when
cryptogenic. However, there is minimal evidence supporting a significant association …

Thrombophilia is a generic term that defines an increased propensity toward thrombosis and
associated morbidity. Factor V Leiden (FVL; G1691A) and the prothrombin gene mutation …

Objective: Resistance to activated protein C (APC) has been identified as a risk factor for
thrombotic disease in adults. In over 90% of cases, the basis for the APC resistance is a …

Hypercoagulability can pose a significant problem in microsurgical reconstruction. Here, the
authors provide a comprehensive review of macrovascular and microvascular clotting …

Summary While Factor V (FV) Leiden is a risk factor for venous thromboembolism (VTE), the
incidence of VTE among FV Leiden carriers is uncertain. The objective of the study was to …