Repurposing old drugs in oncology: Opportunities with clinical and regulatory challenges ahead

RR Shah, PD Stonier - Journal of clinical pharmacy and …, 2019 - Wiley Online Library
What is known and objective In order to expedite the availability of drugs to treat cancers in a
cost‐effective manner, repurposing of old drugs for oncological indications is gathering …

Methods and related compositions for the treatment of cancer

TA Thompson, D Mackenzie, TI Oprea, LA Sklar… - US Patent …, 2014 - Google Patents
(57) ABSTRACT A method of treatment and/or prevention of cancer comprises administering
agents which cause increased intracellular granularity in cancer cells, at least in an amount …

Murine and human hematopoietic colony formation: a possible regulatory role for intracellular histamine

M Bencsath, J Gidali, LJ Brandes… - Acta Biologica Hungarica, 2002 - akjournals.com
Increasing number of data suggests that locally produced histamine is involved in regulation
of hematopoiesis. In this study the granulocyte/macrophage (CFU-GM) colony formation by …

[PDF][PDF] Formulation and dissolution assessment of a novel repeat action tablet containing a decongestant and an antihistamine

JJ Verner - 2000 - commons.ru.ac.za
These dosage forms facilitate patient compliance by simplifying the dosage regimen, and
decrease the risk of adverse effects by reducing large fluctuations in the plasma …

Methods and related compositions for the treatment of cancer

TA Thompson, D Mackenzie, TI Oprea, LA Sklar… - US Patent …, 2016 - Google Patents
8,287,851 B2 10/2012 Wright et al. 8,314,077 B2 11/2012 Webb et al. 8.338, 464 B2
12/2012 Melnicket al. 8,362,075 B2 1/2013 Lewis et al. 8.420, 665 B2 4/2013 Huang et al …

[CITATION][C] Report Conclusions

S CIU