The medical treatment of Cushing's syndrome

JW Miller, L Crapo - Endocrine Reviews, 1993 - academic.oup.com
I. Introduction W ITH the advent of synthetic glucocorticoids in the late 1940s, adrenalectomy
ushered in the modern era of treatment for Cushing's syndrome. Nearly two decades later …

Therapy of Cushing's syndrome with steroid biosynthesis inhibitors

D Engelhardt, MM Weber - The Journal of steroid biochemistry and …, 1994 - Elsevier
Several substances with different inhibitory effects on adrenal steroid biosynthesis were
investigated in patients with Cushing's syndrome. It has been shown that trilostane, a 3β …

Use of ketoconazole in the treatment of Cushing's disease and ectopic ACTH syndrome

A Tabarin, A Navarranne, J Guerin… - Clinical …, 1991 - Wiley Online Library
Ketoconazole, an imidazole derivative which Inhibits adrenal steroidogenesis, has been
used with success for the metabolic control of Cushing's disease. Few data are available …

Cytotoxic treatment of adrenocortical carcinoma

H Ahlman, A Khorram-Manesh, S Jansson… - World journal of …, 2001 - Springer
Adrenocortical carcinoma (ACC) is a rare, aggressive tumor that is often detected in an
advanced stage. Medical treatment with the adrenotoxic drug mitotane has been used for …

Adrenocortical carcinoma

SE Rodgers, DB Evans, JE Lee… - Surgical Oncology …, 2006 - surgonc.theclinics.com
Adrenocortical carcinoma (ACC) is a rare disease with a worldwide incidence of 0.5 to 2 per
1 million people annually [1, 2]. It occurs most commonly in adults in their fourth and fifth …

Steroid biosynthesis inhibitors in Cushing's syndrome

D Engelhardt - The clinical investigator, 1994 - Springer
Conclusions About one-third of all patients with Cushing's syndrome cannot be cured by
surgery (at the pituitary or adrenal level) or radiation therapy and are therefore candidates …

Inhibition of steroidogenesis by ketoconazole. Therapeutic uses

P Miossec, F Archambeaud-Mouveroux… - Annales d' …, 1997 - europepmc.org
Ketoconazole, a broad-spectrum imidazole antimycotic agent, interferes with cytochrome P-
450 enzyme systems in several organs (testis, ovary, adrenal gland, kidney, liver). It inhibits …

Favourable response of a virilizing adrenocortical carcinoma to preoperative treatment with ketoconazole and postoperative chemotherapy

JW Kruimel, AG Smals, LV Beex… - European Journal of …, 1991 - academic.oup.com
A 25-year-old woman presented with an extensive adrenocortical carcinoma with severe
virilization and mild Cushing's syndrome. In the tumour there was a primacy of the P450C17 …

[HTML][HTML] Tratamiento farmacológico del síndrome de Cushing

JJ Díez - Revista Cubana de Medicina, 1999 - scielo.sld.cu
Tratamiento farmacológico del síndrome de Cushing SciELO - Scientific Electronic Library
Online vol.38 número1 Marcadores biológicos para el diagnóstico y tratamiento del asma …

[PDF][PDF] Фармакотерапія патологічних станів надниркових залоз

ЯГ Бальон - Журнал органічної та фармацевтичної хімії, 2012 - dspace.nbuv.gov.ua
Надниркові залози–парний орган, який складається з правої і дещо меншої по масі і
розмірах лівої залоз, розміщений ретроперитонеально над верхніми полюсами нирок …