Safety issues concerning the use of disulfiram in treating alcohol dependence
J Chick - Drug Safety, 1999 - Springer
Disulfiram is known to cause hepatitis, which is sometimes fatal. The best estimate of the
frequency of disulfiram-induced fatal hepatitis is 1 case in 30 000 patients treated/year. Its …
frequency of disulfiram-induced fatal hepatitis is 1 case in 30 000 patients treated/year. Its …
Disulfiram: mechanisms, applications, and challenges
J Lanz, N Biniaz-Harris, M Kuvaldina, S Jain, K Lewis… - Antibiotics, 2023 - mdpi.com
Background: Since disulfiram's discovery in the 1940s and its FDA approval for alcohol use
disorder, other indications have been investigated. This review describes potential clinical …
disorder, other indications have been investigated. This review describes potential clinical …
Disulfiram (Tetraethylthiuram Disulfide) in the treatment of lyme disease and babesiosis: report of experience in three cases
KB Liegner - Antibiotics, 2019 - mdpi.com
Three patients, each of whom had required intensive open-ended antimicrobial therapy for
control of the symptoms of chronic relapsing neurological Lyme disease and relapsing …
control of the symptoms of chronic relapsing neurological Lyme disease and relapsing …
Inhibition of GSDMD activation by Z-LLSD-FMK or Z-YVAD-FMK reduces vascular inflammation and atherosclerotic lesion development in ApoE−/− mice
BL Zhang, P Yu, EY Su, CY Zhang, SY Xie… - Frontiers in …, 2023 - frontiersin.org
Pyroptosis is a form of pro-inflammatory cell death that can be mediated by gasdermin D
(GSDMD) activation induced by inflammatory caspases such as caspase-1. Emerging …
(GSDMD) activation induced by inflammatory caspases such as caspase-1. Emerging …
[HTML][HTML] Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram
M Beutler, J Harnischfeger, MHW Weber… - European Journal of …, 2023 - Elsevier
Schistosomiasis is an infectious disease caused by blood flukes of the genus Schistosoma
and affects approximately 200 million people worldwide. Since Praziquantel (PZQ) is the …
and affects approximately 200 million people worldwide. Since Praziquantel (PZQ) is the …
Disulfiram neuropathy: two cases of distal axonopathy
M Filosto, M Tentorio, L Broglio, S Buzio… - Clinical …, 2008 - Taylor & Francis
Background. Disulfiram may cause a peripheral neuropathy that is considered dose-and
duration-of-exposure-related. Axonal degeneration has been described as a pathological …
duration-of-exposure-related. Axonal degeneration has been described as a pathological …
Disulfiram-induced neuropathy: a case report
S Mohapatra, MR Sahoo, N Rath - General hospital psychiatry, 2015 - Elsevier
Disulfiram is widely used for aversive treatment of alcoholism. Neuropathy is one of the most
severe side effects of disulfiram therapy. We report the case of a young man who developed …
severe side effects of disulfiram therapy. We report the case of a young man who developed …
Reversible, late‐onset disulfiram‐induced neuropathy and encephalopathy
D Borrett, P Ashby, J Bilbao… - Annals of Neurology …, 1985 - Wiley Online Library
Disulfiram toxicity is a well‐recognized cause of peripheral neuropathy and encephalopathy,
usually developing within a few months of the start of therapy. We describe a patient who …
usually developing within a few months of the start of therapy. We describe a patient who …
Enzyme and behavioral changes in young chicks as a result of carbaryl treatment
M Farage‐Elawar - … of Toxicology and Environmental Health, Part A …, 1989 - Taylor & Francis
Certain biochemical and behavioral effects of carbaryl were investigated in chicks. Six‐day‐
old birds received 100 mg/kg body weight (bw) per day carbaryl for 7 d. Brain …
old birds received 100 mg/kg body weight (bw) per day carbaryl for 7 d. Brain …
CarbamicAcidEsterInsecticides
DJ Ecobichon - Pesticides and Neurological Diseases, 1993 - taylorfrancis.com
In addition to the above compounds, several derivatives have been synthesized, with sulfur
substitutions at the ester and/or the ether oxygen in carl> amic acid, producing thio-or …
substitutions at the ester and/or the ether oxygen in carl> amic acid, producing thio-or …