The abuse of analgesics in the Australian community and its role in disease of the heart and
alimentary canal has been recognized since 1907 [1] when it was noted that “what the drink …

The weight of clinical evidence linking analgesic abuse with chronic renal disease is
overwhelming and analgesic nephropathy continues to be an important problem. The …

The association between heavy consumption of analgesics and nephropathy was first
described in Canada in 1961 [1]. Thirty-seven such patients were reported in 1968 [2, 3] …

Background and objectives: This study examined age-specific incidence and prevalence of
renal replacement therapy attributed to analgesic nephropathy from 1971 through 2005 and …

Most antipyretic analgesics can cause acute nephrotoxic effects, including acute tubular
necrosis, acute interstitial nephritis, glomerular toxicity, and functional changes, such as …

Although the question of whether or not analgesic abuse leads to a certain type of
nephropathy has been investigated since 1953, no conclusive answer has been …

Drugs commonly used for diagnostic and therapeutic purposes may cause toxic
nephropathy. There are several factors that account for renal susceptibility. Precise …

Twenty-three patients with analgesic nephropathy and apparent cessation of drug abuse
were tested for blood acetaminophen and salicylate on the occasion of routine renal control …

The factors that influence the progression of renal failure in analgesic-associated
nephropathy (AAN) still remain to be clarified. In this study, the actual analgesic intake (N …

There are many causes of interstitial nephritis other than pyelonephritis. The term interstitial
nephritis does not connote a single etiologic or pathogenetic mechanism; it rather arbitrarily …