Excerpt Ergot alkaloid preparations such as ergotamine (Cafergot, Sandoz, East Hanover,
New Jersey) and methysergide (Sansert, Sandoz) are used to treat migraine headache …

Nowadays, guidelines are derived from the findings of randomized controlled therapeutic
trials. However, an overall significant P value does not exclude that some patients may be …

Ergotamine has been associated with numerous vascular complications but only rarely with
fibrosing disorders or valvular heart disease. Two patients are described in whom severe …

Methysergide (Sansert) is known to cause mitral and aortic valvular fibrosis and dysfunction,
but has generally not been known to damage right heart valves or the myocardium, and …

Serotonin plays a significant role in the development of carcinoid heart disease, which
primarily leads to fibrosis and contraction of right-sided heart valves. Recently, strong …

Appetite suppressant-related pulmonary hypertension and valvular heart disease are
established disorders. Currently, the mechanism of these disorders is not certain. An …

Mitral REGURGITATION is a common form of valvular heart disease which usually presents
little difficulty in diagnosis. Its hemodynamic importance was first emphasized in I803 by the …

Methysergide (Sansert) has been associated with numerous fibrotic disorders. In particular,
multiple cardiac lesions have been described in cases where methysergide was thought to …

Background Anorectic drugs are overlooked as a cause of valvular heart disease (VHD).
Aim To describe the characteristics of a large population of patients with severe VHD who …

This case report concerns a woman treated continuously since at least 10 years by
methysergide for cluster headache. The echocardiographic and histological features of the …