Control of severe pain with sustained-release morphine tablets v. oral morphine solution.

WW Arkinstall, BR Goughnour, JA White… - CMAJ: Canadian …, 1989 - ncbi.nlm.nih.gov
Recently a sustained-release morphine sulfate tablet (MS Contin [MSC]) was introduced in
Canada. In a randomized double-blind crossover trial we compared MSC given every 12 …

Analgesic response to single and multiple doses of controlled‐release morphine tablets and morphine oral solution in cancer patients

BR Goughnour, WW Arkinstall, JH Stewart - Cancer, 1989 - Wiley Online Library
Immediate‐release oral morphine, given every four hours in individually titrated doses, is
effective in the control of severe cancer pain. To evaluate the analgesic efficacy of a controlled‐…

Randomized evaluation of controlled-release codeine and placebo in chronic cancer pain

HS Dhaliwal, P Sloan, WW Arkinstall… - Journal of pain and …, 1995 - Elsevier
Codeine is widely used in combination with acetaminophen and aspirin for the management
of mild to moderate pain. However, there are few controlled clinical trials of single-entity …

Once-daily sustained-release theophylline reduces diurnal variation in spirometry and symptomatology in adult asthmatics

WW Arkinstall, ME Atkins, D Harrison… - American Review of …, 1987 - atsjournals.org
In 22 adult asthmatics (mean age, 55.2 ± 15.4 yr), we compared Uniphyl given once a day
to Theo-Dur given twice a day using a randomized, double-blind, two-phase crossover trial. …

Review of the North American experience with evening administration of Uniphyl tablets, a once-daily theophylline preparation, in the treatment of nocturnal asthma

WW Arkinstall - The American Journal of Medicine, 1988 - Elsevier
Increasing awareness of the exaggerated circadian rhythm in bronchomotor tone that causes
most asthmatic patients to have increased respiratory symptoms in the early morning has …

Potential cost-avoidance with oral extended-release morphine sulfate tablets versus morphine sulfate solution

BR Goughnour, WW Arkinstall - American journal of hospital …, 1991 - academic.oup.com
The costs of acquiring, preparing, and administering morphine sulfate extended-release tablets
and morphine sulfate solution were compared. Pharmacists at an acute-care community …

Interaction between physicians and the pharmaceutical industry.

WW Arkinstall - CMAJ: Canadian Medical Association Journal, 1995 - ncbi.nlm.nih.gov
FOR OLD Q,UOTATION Page 1 tions of physician mobility are a disservice to the public
interest, what sort of service do we offer the public if young students may progress through …

Regulation of fuel metabolism by preexercise muscle glycogen content and exercise intensity

MJ Arkinstall, CR Bruce, SA Clark… - Journal of applied …, 2004 - journals.physiology.org
To date, the results of studies that have examined the effects of altering preexercise muscle
glycogen content and exercise intensity on endogenous carbohydrate oxidation are …

Putting together the pieces of the physician supply puzzle

WW Arkinstall - CMAJ, 2000 - Can Med Assoc
Anewspaper recently claimed that in 1998, children in some parts of British Columbia were
being prescribed methylphenidate (Ritalin) at the highest known rate in North America. 1 This …

Clinical Evaluation of a New Theophylline Strategy: Evening Dosing with Once a Day Uniphyl

WW Arkinstall, ME Atkins, D Harrison… - … heute: 5. Internationaler …, 1987 - Springer
Asthmatic characteristics demonstrate a circadian variation in airway calibre; airflow is generally
maximum in the afternoon and early evening, and reduced at night and early morning [1]…