User profiles for Wendy Wong
 | Wendy SW WongNCI Verified email at cornell.edu Cited by 10297 |
Rate of de novo mutations and the importance of father's age to disease risk
…, A Jonasdottir, A Jonasdottir, WSW Wong… - Nature, 2012 - nature.com
Mutations generate sequence diversity and provide a substrate for selection. The rate of de
novo mutations is therefore of major importance to evolution. Here we conduct a study of …
novo mutations is therefore of major importance to evolution. Here we conduct a study of …
Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs
Motivation: Whole genome and exome sequencing of matched tumor–normal sample pairs
is becoming routine in cancer research. The consequent increased demand for somatic …
is becoming routine in cancer research. The consequent increased demand for somatic …
Bayes empirical Bayes inference of amino acid sites under positive selection
Codon-based substitution models have been widely used to identify amino acid sites under
positive selection in comparative analysis of protein-coding DNA sequences. The …
positive selection in comparative analysis of protein-coding DNA sequences. The …
Linear ubiquitination prevents inflammation and regulates immune signalling
Members of the tumour necrosis factor (TNF) receptor superfamily have important functions
in immunity and inflammation. Recently linear ubiquitin chains assembled by a complex …
in immunity and inflammation. Recently linear ubiquitin chains assembled by a complex …
Accuracy and power of statistical methods for detecting adaptive evolution in protein coding sequences and for identifying positively selected sites
The parsimony method of Suzuki and Gojobori (1999) and the maximum likelihood method
developed from the work of Nielsen and Yang (1998) are two widely used methods for …
developed from the work of Nielsen and Yang (1998) are two widely used methods for …
The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse
…, C Fernandes, D Miyazawa, W Wong… - Proceedings of the …, 2006 - National Acad Sciences
Rhodococcus sp. RHA1 (RHA1) is a potent polychlorinated biphenyl-degrading soil actinomycete
that catabolizes a wide range of compounds and represents a genus of considerable …
that catabolizes a wide range of compounds and represents a genus of considerable …
[PDF][PDF] The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity
Nucleotide-binding and oligomerization domain (NOD)-like receptors constitute a first line of
defense against invading bacteria. X-linked Inhibitor of Apoptosis (XIAP) is implicated in the …
defense against invading bacteria. X-linked Inhibitor of Apoptosis (XIAP) is implicated in the …
[BOOK][B] Internal affairs: How the structure of NGOs transforms human rights
WH Wong - 2017 - degruyter.com
… League of Human Rights—Wendy H. Wong demonstrates that NGOs that choose to …
right" cause or have the most resources, Wong shows that how NGOs make and implement …
right" cause or have the most resources, Wong shows that how NGOs make and implement …
[HTML][HTML] Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer
The Tasmanian devil (Sarcophilus harrisii), the largest marsupial carnivore, is endangered
due to a transmissible facial cancer spread by direct transfer of living cancer cells through …
due to a transmissible facial cancer spread by direct transfer of living cancer cells through …
Parent-of-origin-specific signatures of de novo mutations
De novo mutations (DNMs) originating in gametogenesis are an important source of genetic
variation. We use a data set of 7,216 autosomal DNMs with resolved parent of origin from …
variation. We use a data set of 7,216 autosomal DNMs with resolved parent of origin from …
