Isolation, Structure Elucidation, and Synthesis of Cytotoxic Tryptanthrin Analogues from Phaius mishmensis

CW Jao, WC Lin, YT Wu, PL Wu - Journal of natural products, 2008 - ACS Publications
Bioassay-guided chromatographic separation of the cytotoxic MeOH extract of Phaius
mishmensis led to the isolation of two known and six new indoloquinazolinones, phaitanthrins A−…

Plasma free amino acid profile in cancer patients

HS Lai, JC Lee, PH Lee, ST Wang, WJ Chen - Seminars in cancer biology, 2005 - Elsevier
Redistribution or translocation of plasma free amino acids (PFAAs) to support visceral or
tumor protein synthesis is an essential feature in cancer patients. An abnormal PFAA profile …

Long-term prognosis of patients with biliary atresia: a 25 year summary

PY Hung, CC Chen, WJ Chen, HS Lai… - Journal of pediatric …, 2006 - journals.lww.com
Objective: The purpose of this study was to delineate the long-term prognosis of biliary atresia
(BA) in Taiwan. Study Design: From 1976 to 2000, 185 children were diagnosed with BA, …

Free radical scavenging activity of fullerenol on the ischemia-reperfusion intestine in dogs

HS Lai, WJ Chen, LY Chiang - World journal of surgery, 2000 - Springer
Fullerenol, a water-soluble C 60 -fullerene derivative, has been demonstrated to have the
capability to scavenge free radicals in vitro and in vivo. The purpose of this study was to …

Resveratrol-induced cellular apoptosis and cell cycle arrest in neuroblastoma cells and antitumor effects on neuroblastoma in mice

Y Chen, SH Tseng, HS Lai, WJ Chen - Surgery, 2004 - Elsevier
BACKGROUND: The prognosis of neuroblastoma patients remains unsatisfactory. Therefore,
developing an effective treatment strategy is important. Resveratrol, a natural polyphenol, …

Predictive equations for basal metabolic rate in Chinese adults: a cross-validation study

HY Liu, YF Lu, WJ Chen - Journal of the American Dietetic Association, 1995 - Elsevier
Objective To develop predictive equations for basal metabolic rate (BMR) in healthy Chinese
adults and to evaluate factors that may influence BMR. Design Measuring the BMR of …

Indole Alkaloids from Cephalanceropsis gracilis

PL Wu, YL Hsu, CW Jao - Journal of natural products, 2006 - ACS Publications
Purification of CHCl 3 and EtOAc solubles of the MeOH extract of Cephalanceropsis gracilis
afforded seven new indole alkaloids, cephalinones A (1), B (2), C (3), and D (4) and …

IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1

MT Lin, CY Juan, KJ Chang, WJ Chen… - Carcinogenesis, 2001 - academic.oup.com
Apoptosis plays a critical role in maintaining genomic integrity by selectively removing the
most heavily damaged cells from the population. Reactive oxygen species (ROS) and certain …

Cyr61 induces gastric cancer cell motility/invasion via activation of the integrin/nuclear factor-κB/cyclooxygenase-2 signaling pathway

MT Lin, CY Zuon, CC Chang, ST Chen, CP Chen… - Clinical cancer …, 2005 - AACR
Purpose: Cysteine-rich 61 (Cyr61/CCN1) is involved in many different types of tumor development
and progression. Nonetheless, the role of Cyr61 in human gastric cancer has not yet …

Selective use of ultrasonography for the detection of pneumoperitoneum

SC Chen, HP Wang, WJ Chen, FY Lin… - Academic …, 2002 - Wiley Online Library
Objective: Whether ultrasonography is superior to plain radiography for the detection of
pneumoperitoneum is unknown. The goal of this study was to determine the value of …