T lymphocytes are the central regulatory cells of the immune system. Much of their function
is mediated by a set of small proteins whose expression, secretion, or both is induced as a …

Multipotential naive CD4 + T cells differentiate into distinct lineages including T helper 1 (Th1),
Th2, Th17, and inducible T regulatory (iTreg) cells. The remarkable diversity of CD4 + T …

Injection of anti-CD3 antibodies causes prompt expression of interleukin (IL)-4, IL-2, and
interferon gamma (IFN-gamma) mRNA among spleen cells. The optimal dose of anti-CD3 for …

Our previous work demonstrated that cytotoxic T lymphocyte (CTL)-mediated tumor
immunosurveillance of the 15-12RM tumor could be suppressed by a CD1d-restricted lymphocyte, …

CD4 T cells play critical roles in mediating adaptive immunity to a variety of pathogens.
They are also involved in autoimmunity, asthma, and allergic responses as well as in tumor …

This standard-setting textbook has defined the field of immunology since 1984, and is now
in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage …

Gamma interferon (IFN-γ) and B cell stimulatory factor-1 (BSF-1), also known as interleukin-4,
are T cell-derived lymphokines that have potent effects on B cell proliferation and …

In 1986, Mosmann and Coffman identified 2 subsets of activated CD4 T cells, Th1 and Th2
cells, which differed from each other in their pattern of cytokine production and their functions. …

Contrary to widespread assumption, dynamic RAM (DRAM), the main memory in most
modern computers, retains its contents for several seconds after power is lost, even at room …

▪ Abstract Interleukin-4 is a multifunctional cytokine that plays a critical role in the regulation
of immune responses. Its effects depend upon binding to and signaling through a receptor …