Cardiac fibroblast (CF) proliferation and differentiation into hypersecretory myofibroblasts
can lead to excessive extracellular matrix (ECM) production and cardiac fibrosis. In turn, the …

One in eight American women develops breast cancer. Of the many patients requiring
mastectomy yearly as a consequence, most elect some form of breast reconstruction. Since 2006, …

A ligand epitope antigen presentation system (LEAPS™) heteroconjugate vaccine containing
a CTL epitope (H1) from the HSV-1 immediate early protein ICP27 (322–332) and a …

… The observations described above sup- port the theory that alcobol-induced pancreatic
injury in the 484 HORNE AND TSUKAMOTO presence of a high fat diet is brought about by a …

As a potential means of comparing hypothyroidism in humans, this work intended to establish
a defined hypothyroid state in immature miniature swine and evaluate specific molecular, …

Background: The effect of compression on the physis is generally defined by the Hueter-Volkmann
principle, in which decreased linear growth of the physis results from increased …

… The substitution in this equation of the maximum value of wi/m3 gives finally the maximum
… the principle of ‘maximum energy transmission’ (Horne 1965). The proof of this principle pre …

Background Mitochondria are sensitive indicators of cellular pathology. Under certain
circumstances, these organelles respond to cellular insult by a marked increase in size, resulting …

Even though in vivo studies of mastication in living primates are often used to test functional
and adaptive hypotheses explaining primate masticatory behavior, we currently have little …

The alveolar epithelium plays a critical role in resolving pulmonary edema. We thus hypothesized
that its function might be upregulated in rats with heart failure, a condition that severely …