[HTML][HTML] Vitamin D supplementation associated to better survival in hospitalized frail elderly COVID-19 patients: the GERIA-COVID quasi-experimental study

G Annweiler, M Corvaisier, J Gautier, V Dubée… - Nutrients, 2020 - mdpi.com
Background. The objective of this quasi-experimental study was to determine whether bolus
vitamin D supplementation taken either regularly over the preceding year or after the …

[HTML][HTML] Utility of hyposmia and hypogeusia for the diagnosis of COVID-19

…, C Declerck, C Paillé, M Revest, V Dubée… - The Lancet Infectious …, 2020 - thelancet.com
1 Guan W, Ni Z, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N
Engl J Med 2020; published online Feb 28. DOI: 10.1056/NEJMoa2002032. 2 Hopkins C, …

Assessment of SARS-CoV-2 serological tests for the diagnosis of COVID-19 through the evaluation of three immunoassays: Two automated immunoassays …

…, O Serri, A Pivert, F Joubaud, V Dubée… - Journal of Clinical …, 2020 - Elsevier
Background The emergence of new SARS-CoV-2 has promoted the development of new
serological tests that could be complementary to RT-PCR. Nevertheless, the assessment of …

Inactivation of Mycobacterium tuberculosis l,d-Transpeptidase LdtMt1 by Carbapenems and Cephalosporins

V Dubée, S Triboulet, JL Mainardi… - Antimicrobial agents …, 2012 - Am Soc Microbiol
The structure of Mycobacterium tuberculosis peptidoglycan is atypical since it contains a
majority of 3→3 cross-links synthesized by l,d-transpeptidases that replace 4→3 cross-links …

In Vitro Cross-Linking of Mycobacterium tuberculosis Peptidoglycan by l,d-Transpeptidases and Inactivation of These Enzymes by Carbapenems

M Cordillot, V Dubée, S Triboulet… - Antimicrobial agents …, 2013 - Am Soc Microbiol
The Mycobacterium tuberculosis peptidoglycan is cross-linked mainly by l,d-transpeptidases
(LDTs), which are efficiently inactivated by a single β-lactam class, the carbapenems. …

β-Lactamase inhibition by avibactam in Mycobacterium abscessus

V Dubée, A Bernut, M Cortes, T Lesne… - Journal of …, 2015 - academic.oup.com
Objectives Two β-lactams, cefoxitin and imipenem, are part of the reference treatment for
pulmonary infections with Mycobacterium abscessus. M. abscessus has recently been shown …

[HTML][HTML] COvid-19 and high-dose VITamin D supplementation TRIAL in high-risk older patients (COVIT-TRIAL): study protocol for a randomized controlled trial

…, M Beaudenon, J Gautier, R Simon, V Dubée… - Trials, 2020 - Springer
Background With the lack of effective therapy, chemoprevention, and vaccination against
SARS-CoV-2, focusing on the immediate repurposing of existing drugs gives hope of curbing …

Characterization of broad-spectrum Mycobacterium abscessus class A β-lactamase

D Soroka, V Dubée, O Soulier-Escrihuela… - Journal of …, 2014 - academic.oup.com
Objectives Imipenem and cefoxitin are used to treat Mycobacterium abscessus infections and
have moderate activity against this fast-growing mycobacterium (MIC 50 of 16 and 32 mg/L…

Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic

N Dhar, V Dubée, L Ballell, G Cuinet… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Recent clinical studies indicate that meropenem, a β-lactam antibiotic, is a promising candidate
for therapy of drug-resistant tuberculosis. However, meropenem is chemically unstable, …

[HTML][HTML] Hydroxychloroquine in mild-to-moderate coronavirus disease 2019: a placebo-controlled double blind trial

…, JP Talarmin, E Gaigneux, P Motte-Vincent… - Clinical Microbiology …, 2021 - Elsevier
Objectives To determine whether hydroxychloroquine decreases the risk of adverse outcome
in patients with mild to moderate coronavirus disease 2019 (COVID-19) at high risk of …