Use of HLA-B* 58: 01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study

…, SC Hsieh, JC Tsai, WT Lai, WC Tsai, GD Yin, TT Ou… - Bmj, 2015 - bmj.com
… , and were referred to an alternate drug treatment or advised to continue with their prestudy
… from all participants or from parents or guardians for participants aged 21 years or younger. …

Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus

SC Lin, JH Yen, JJ Tsai, WC Tsai, TT Ou… - Arthritis & …, 2004 - Wiley Online Library
Objective. The expression of autoimmunity in mice deficient in programmed death 1 (PD‐1)
suggests that PD‐1 is a candidate gene involved in the development of human autoimmune …

Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis

CC Liu, TJ Fang, TT Ou, CC Wu, RN Li, YC Lin… - Immunology letters, 2011 - Elsevier
OBJECTIVES: To investigate the associations of DNA methylation levels and mRNA expressions
of DNA cytosine-5-methyltransferase 1 (DNMT1) and methyl CpG-binding domain 2 (…

[HTML][HTML] Long-term frequent use of non-steroidal anti-inflammatory drugs might protect patients with ankylosing spondylitis from cardiovascular diseases: a nationwide …

WC Tsai, TT Ou, JH Yen, CC Wu, YC Tung - PLoS One, 2015 - journals.plos.org
The objective of this case-control study was to investigate the risk of cardiovascular disease
(CVD) following non-steroidal anti-inflammatory drug (NSAID) use in patients with …

Acute allergen-induced airway remodeling in atopic asthma

S Phipps, F Benyahia, TT Ou, J Barkans… - American journal of …, 2004 - atsjournals.org
Studies in animals and in human atopic skin suggest that allergen challenge may activate
acute tissue remodeling changes via transforming growth factor–β pathways. We determined …

Associations of a non-synonymous variant in SLC2A9 with gouty arthritis and uric acid levels in Han Chinese subjects and Solomon Islanders

…, S Tovosia, AMS Ko, CH Lee, TT Ou… - Annals of the …, 2010 - ard.bmj.com
Objective To study the associations of gout, tophi and uric acid levels with the gout-related
SLC2A9 (solute carrier family 2, member 9) single nucleotide polymorphisms (SNPs) between …

[HTML][HTML] Dual role of chondrocytes in rheumatoid arthritis: the chicken and the egg

…, YJ Chen, WA Chang, WC Tsai, TT Ou… - International journal of …, 2020 - mdpi.com
Rheumatoid arthritis (RA) is one of the inflammatory joint diseases that display features of
articular cartilage destruction. The underlying disturbance results from immune dysregulation …

Tumor necrosis factor promoter polymorphisms in patients with rheumatoid arthritis in Taiwan.

JH Yen, CJ Chen, WC Tsai, CH Lin, TT Ou… - The journal of …, 2001 - jrheum.org
OBJECTIVE: To investigate the association of tumor necrosis factor (TNF) promoter polymorphisms
with rheumatoid arthritis (RA) in Taiwan. METHODS: TNF promoter polymorphisms at …

[HTML][HTML] The role of macrophages in connective tissue disease-associated interstitial lung disease: focusing on molecular mechanisms and potential treatment …

…, PY Wang, CY Yen, WY Sung, CC Wu, TT Ou… - International Journal of …, 2023 - mdpi.com
… pathways in macrophages or products of macrophages in ILD… in CTD-ILD in investigation
or in clinical trials, as well as the … in preclinical or clinical models of PF or CTD-ILD (Figure 3): …

Programmed death-1 gene polymorphisms in patients with systemic lupus erythematosus in Taiwan

SC Wang, YJ Chen, TT Ou, CC Wu, WC Tsai… - Journal of clinical …, 2006 - Springer
To investigate the role of programmed cell death-1 (PD-1) gene polymorphisms in the
development of systemic lupus erythematosus (SLE) in Taiwan, 109 patients with SLE and 100 …