Calcium antagonistic drugs (also called slow channel or calcium channel inhibitors or calcium
entry blockers) represent a major development in cardiovascular pharmacology. Their …

In the search for abnormalities in hypertensive vessels Ca kinetics was studied in the aorta
of spontaneously hypertensive rats (SHR). The uptake of 45 Ca was significantly less in …

1 The responses to 5‐hydroxytryptamine (5‐HT) of rabbit isolated mesenteric artery and
vein and longitudinal smooth muscle of guinea‐pig ileum were examined in Krebs solution …

This article reviews the types, mechanisms of action and therapeutic applications of currently
used vasodilators. Vasodilators have little value if there is vascular obstruction but are …

In this study we investigated if sodium nitroprusside (NaNP), a vasodilator with direct action
on smooth muscle, would have any effect on calcium kinetics in blood vessels. The effect of …

The effect of renal failure on the excretion and metabolism of 3 H‐reserpine was studied in
15 patients. The plasma level and urinary and fecal exeretion of the drug were followed for 7 …

The effect of hydrochlorothiazide on vascular reactivity to various drugs was studied in rabbit
and dog. In rabbit, dose response in the mesenteric artery and vein was examined in vitro …

The effect of the antihypertensive drug, diazoxide, on peripheral arteries and veins was
investigated in man, dog, and rabbit. The action of diazoxide, 300 mg. given intravenously, was …

METHODS Ten men and 10 women, healthy, informed, consenting volunteers, were studied.
Their mean age was 27.1 years (range 18-50). None were regular users of alcohol or drugs…

Twenty patients with angina pectoris received propranolol hydrochloride at two dosage levels
and placebo in a double-blind trial. The lower dosage of propranolol hydrochloride (80 mg/…