Timely molecular diagnosis of RB1 mutations enables earlier treatment, lower risk, and
better health outcomes for patients with retinoblastoma; empowers families to make informed …

Purpose To establish the recommended phase II dose of the oral γ-secretase inhibitor
RO4929097 (RO) in combination with gemcitabine; secondary objectives include the evaluation of …

Objectives Cisplatin-induced ototoxicity is a common permanent consequence of curative
chemoradiation for locally advanced head and neck squamous cell carcinoma (HNSCC). …

Small cell carcinomas (SCC) most commonly arise from the lung. 1 These tumours are
aggressive, present with early metastasis and are associated with a poorer prognosis compared …

Background: Physician decision-making and perceptions of patients are affected by a
patient's socioeconomic status (SES). We sought to determine if the perceptions of first- and …

Penile cancer occurs in about 1 in 100 000 men annually in developed countries. 1 In
Canada, penile cancer is reported under “genito-urinary, other and unspecified” in the annual …

Colorectal cancer (CRC) is the third most common type of cancer diagnosed in Canada, and
is the leading cause of cancer-related deaths in nonsmokers. Although CRC is considered …

Maintaining faculty vitality Page 1 Maintaining faculty vitality in the face of heavy teaching loads
and the unrelenting challenge of underprepared students requires conscious efort and planning …

Urothelial carcinoma remains an important oncologic problem with significant morbidity and
mortality. This article provides an overview of the current status of treatment of urothelial …

Methods: A web-based questionnaire was e-mailed to physicians treating GU cancers in
Canada, including urologists, radiation oncologists, and medical oncologists. Five domains …