User profiles for Susan Kirkland

Susan Kirkland

Professor of Community Health and Epidemiology, Dalhousie University
Verified email at dal.ca
Cited by 13433

Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.

H Sheng, J Shao, SC Kirkland… - The Journal of …, 1997 - Am Soc Clin Investig
A considerable amount of evidence collected from several different experimental systems
indicates that cyclooxygenase-2 (COX-2) may play a role in colorectal tumorigenesis. Large …

Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people

K Rockwood, S Kirkland, DB Hogan… - Archives of …, 2002 - jamanetwork.com
Background Recent reports suggest a possibly protective effect for statins in patients with
Alzheimer disease. This association could be due to indication bias, ie, people who elect to …

A comprehensive view of sex-specific issues related to cardiovascular disease

…, J Cox, WA Ghali, S Grace, P Hamet, T Ho, S Kirkland… - Cmaj, 2007 - Can Med Assoc
Cardiovascular disease (CVD) is the leading cause of mortality in women. In fact, CVD is
responsible for a third of all deaths of women worldwide and half of all deaths of women over …

The Canadian longitudinal study on aging (CLSA)

PS Raina, C Wolfson, SA Kirkland… - Canadian Journal on …, 2009 - cambridge.org
Canadians are living longer, and older persons are making up a larger share of the population
(14% in 2006, projected to rise to 20% by 2021). The Canadian Longitudinal Study on …

[PDF][PDF] Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

…, C Hastie, MV Holmes, T Illig, SA Kirkland… - The American Journal of …, 2012 - cell.com
Genome-wide association studies (GWASs) have identified many SNPs underlying
variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid …

Frailty in NHANES: comparing the frailty index and phenotype

J Blodgett, O Theou, S Kirkland, P Andreou… - Archives of gerontology …, 2015 - Elsevier
The two most commonly employed frailty measures are the frailty phenotype and the frailty
index. We compared them to examine whether they demonstrated common characteristics of …

Cohort profile: the Canadian longitudinal study on aging (CLSA)

P Raina, C Wolfson, S Kirkland… - International journal …, 2019 - academic.oup.com
The Canadian Longitudinal Study on Aging (CLSA) was established to understand and
address the needs of an aging population. 1–3 Overall aims are to examine aging as a dynamic …

Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon …

…, PJ Dempsey, R Chinery, SC Kirkland… - Proceedings of the …, 1997 - National Acad Sciences
Nonsteroidal antiinflammatory drugs reduce the risk of colon cancer, possibly via
cyclooxygenase (COX) inhibition. The growth factor-inducible COX-2, which is overexpressed in …

Wheelchair-related accidents caused by tips and falls among noninstitutionalized users of manually propelled wheelchairs in Nova Scotia

…, MG Brown, SA Kirkland… - American Journal of …, 1994 - journals.lww.com
The purpose of this study was to document what proportion of noninstitutionalized users of
manually propelled wheelchairs are affected by wheelchair-related accidents caused by tips …

[PDF][PDF] Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

…, MH Hofker, GK Hovingh, DS Kim, SA Kirkland… - The American Journal of …, 2014 - cell.com
Blood pressure (BP) is a heritable risk factor for cardiovascular disease. To investigate
genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), …