Tiotropium in combination with placebo, salmeterol, or fluticasone–salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial

…, HB Prins, G Ford, D Bleskie, S Doucette… - Annals of internal …, 2007 - acpjournals.org
Background: Treatment of moderate or severe chronic obstructive pulmonary disease (COPD)
with combinations of inhaled corticosteroids, long-acting β-agonists, and long-acting …

How quickly do systematic reviews go out of date? A survival analysis

…, M Sampson, MT Ansari, J Ji, S Doucette… - Annals of internal …, 2007 - acpjournals.org
Background: Systematic reviews are often advocated as the best source of evidence to guide
clinical decisions and health care policy, yet we know little about the extent to which they …

[HTML][HTML] Hypothermia therapy after traumatic brain injury in children

…, DJ Bohn, PB Dirks, S Doucette… - … England Journal of …, 2008 - Mass Medical Soc
Background Hypothermia therapy improves survival and the neurologic outcome in animal
models of traumatic brain injury. However, the effect of hypothermia therapy on the …

Association between suicide attempts and selective serotonin reuptake inhibitors: systematic review of randomised controlled trials

D Fergusson, S Doucette, KC Glass, S Shapiro… - Bmj, 2005 - bmj.com
Objective To establish whether an association exists between use of selective serotonin
reuptake inhibitors (SSRIs) and suicide attempts. Design Systematic review of randomised …

Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: a propensity-matched analysis

…, A Kumar, P Dodek, L Kravetsky, S Doucette… - Critical care …, 2010 - journals.lww.com
Background: Septic shock represents the major cause of infection-associated mortality in
the intensive care unit. The possibility that combination antibiotic therapy of bacterial septic …

Does this patient have deep vein thrombosis?

PS Wells, C Owen, S Doucette, D Fergusson, H Tran - Jama, 2006 - jamanetwork.com
ContextOutpatients with suspected deep vein thrombosis (DVT) have nonspecific signs and
symptoms. Missed DVT diagnosis may result in fatal pulmonary embolism. Since many …

Overdiagnosis of asthma in obese and nonobese adults

…, SK Field, GG Alvarez, RE Dales, S Doucette… - Cmaj, 2008 - Can Med Assoc
Background: It is unclear whether asthma is overdiagnosed in developed countries, particularly
among obese individuals, who may be more likely than nonobese people to experience …

[HTML][HTML] Aspirin or rivaroxaban for VTE prophylaxis after hip or knee arthroplasty

…, S Pleasance, P Andreou, S Doucette… - New England journal …, 2018 - Mass Medical Soc
Background Clinical trials and meta-analyses have suggested that aspirin may be effective
for the prevention of venous thromboembolism (proximal deep-vein thrombosis or pulmonary …

[HTML][HTML] A systematic review and meta-analysis of efficacy, cost-effectiveness, and safety of selected complementary and alternative medicine for neck and low-back …

…, C Ammendolia, T Dryden, S Doucette… - Evidence-Based …, 2012 - hindawi.com
Background. Back pain is a common problem and a major cause of disability and health care
utilization. Purpose. To evaluate the efficacy, harms, and costs of the most common CAM …

[HTML][HTML] Cardiac complications in patients with community-acquired pneumonia: a systematic review and meta-analysis of observational studies

…, KN Suh, G Rose, JA Chirinos, S Doucette… - PLoS …, 2011 - journals.plos.org
Background Community-acquired pneumonia (CAP) is a leading cause of morbidity and
mortality. CAP can trigger acute cardiac events. We sought to determine the incidence of major …