OBJECTIVE: To present estimates of the lifetime prevalence of DSM-IV mental disorders
with and without severe impairment, their comorbidity across broad classes of disorder, and …

Importance Mendelian randomization (MR) studies use genetic variation associated with
modifiable exposures to assess their possible causal relationship with outcomes and aim to …

Context Eating disorders are severe conditions, but little is known about the prevalence or
correlates of these disorders from population-based surveys of adolescents. Objectives To …

Mendelian randomisation (MR) studies allow a better understanding of the causal effects of
modifiable exposures on health outcomes, but the published evidence is often hampered by …

Objective: Anorexia nervosa has been consistently associated with increased mortality, but
whether this is true for other types of eating disorders is unclear. The goal of this study was to …

Objective To investigate the association between overeating (without loss of control) and binge
eating (overeating with loss of control) and adverse outcomes. Design Prospective cohort …

Background Late-life depressive symptoms have been extensively studied for their relationship
with incident dementia, but have been typically assessed at a single timepoint. Such an …

Objective: To examine prevalence and clinical correlates of eating disorder not otherwise
specified (EDNOS) in the US population. Method: Two cross‐sectional surveys of adults and …

Objective To investigate whether anorexia nervosa (AN), bulimia nervosa (BN), binge
eating disorder (BED), and other specified feeding and eating disorders (OSFED), including …

Drug repurposing provides a rapid approach to meet the urgent need for therapeutics to
address COVID-19. To identify therapeutic targets relevant to COVID-19, we conducted …