Background Mild cognitive impairment is a transitional state between the cognitive changes
of normal aging and early Alzheimer's disease. Methods In a double-blind study, we …

ContextSeveral reports from small clinical trials have suggested that estrogen replacement
therapy may be useful for the treatment of Alzheimer disease (AD) in women.ObjectiveTo …

Background Mild cognitive impairment (MCI) represents a transitional state between the
cognitive changes of normal aging and very early dementia and is becoming increasingly …

Context Laboratory evidence that inflammatory mechanisms contribute to neuronal injury in
Alzheimer disease (AD), along with epidemiological evidence, suggests that nonsteroidal …

Context Blood levels of homocysteine may be increased in Alzheimer disease (AD) and
hyperhomocysteinemia may contribute to disease pathophysiology by vascular and direct …

Background: Spasticity is a common and poorly controlled symptom of multiple sclerosis.
Our objective was to determine the short-term effect of smoked cannabis on this symptom. …

Objective In preclinical reproductive studies, leflunomide was found to be embryotoxic and
teratogenic. Women treated with leflunomide are advised to avoid pregnancy; those who …

Background Individuals diagnosed as having mild cognitive impairment (MCI) have a high
likelihood of progressing to dementia within 3 to 5 years, but not all individuals with MCI …

In a longitudinal, multicenter study of 4,954 men at risk for human immunodeficiency virus
infection and acquired immunodeficiency syndrome, data from the first 9.5 years of follow-up (…

Objective To estimate the incidence rate and predictors of seizures in patients with mild to
moderate Alzheimer disease (AD). Design Cohort study of patients with mild to moderate AD …