User profiles for Shane Shapera
Shane ShaperaUniversity of Toronto Verified email at uhn.ca Cited by 1926 |
Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled …
…, SA LeClercq, M Hyman, S Shapera… - The Lancet …, 2023 - thelancet.com
Background Interstitial lung disease is a known complication of rheumatoid arthritis, with a
lifetime risk of developing the disease in any individual of 7·7%. We aimed to assess the safety…
lifetime risk of developing the disease in any individual of 7·7%. We aimed to assess the safety…
Ziritaxestat, a novel autotaxin inhibitor, and lung function in idiopathic pulmonary fibrosis: the ISABELA 1 and 2 randomized clinical trials
…, J Morisset, S Provencher, C Ryerson, S Shapera… - Jama, 2023 - jamanetwork.com
Importance There is a major need for effective, well-tolerated treatments for idiopathic
pulmonary fibrosis (IPF). Objective To assess the efficacy and safety of the autotaxin inhibitor …
pulmonary fibrosis (IPF). Objective To assess the efficacy and safety of the autotaxin inhibitor …
Prevalence and characteristics of progressive fibrosing interstitial lung disease in a prospective registry
Background Progressive fibrosing interstitial lung disease (PF-ILD) is characterised by
progressive physiological, symptomatic and/or radiographic worsening. The real-world …
progressive physiological, symptomatic and/or radiographic worsening. The real-world …
Accuracy and reliability of internet resources for information on idiopathic pulmonary fibrosis
…, D O'Connor, AM Flexman, S Shapera… - American journal of …, 2016 - atsjournals.org
Rationale: Patients commonly use the Internet as a resource for health information; however,
no studies have evaluated the online information about idiopathic pulmonary fibrosis (IPF). …
no studies have evaluated the online information about idiopathic pulmonary fibrosis (IPF). …
[HTML][HTML] Acute exacerbations of progressive-fibrosing interstitial lung diseases
…, ML Padilla, J Roman, S Shapera - European …, 2018 - Eur Respiratory Soc
Acute exacerbation of interstitial lung disease (ILD) is associated with a poor prognosis and
high mortality. Numerous studies have documented acute exacerbation in idiopathic …
high mortality. Numerous studies have documented acute exacerbation in idiopathic …
Practical considerations for the diagnosis and treatment of fibrotic interstitial lung disease during the coronavirus disease 2019 pandemic
… Fisher MD g , Nathan Hambly MD h , Martin Kolb MD h , Julie Morisset MD i , Shane
Shapera MD g , Christopher J. Ryerson MD a b … Shapera, T. To, TK Marras, A. Gershon, S. …
Shapera MD g , Christopher J. Ryerson MD a b … Shapera, T. To, TK Marras, A. Gershon, S. …
[HTML][HTML] Phase 2 clinical trial of PBI-4050 in patients with idiopathic pulmonary fibrosis
…, H Manganas, CJ Ryerson, S Shapera… - European …, 2019 - Eur Respiratory Soc
PBI-4050 is a novel orally active small-molecule compound with demonstrated anti-fibrotic
activity in several models of fibrosis, including lung fibrosis. We present results from our first …
activity in several models of fibrosis, including lung fibrosis. We present results from our first …
Procedure volume and mortality after surgical lung biopsy in interstitial lung disease
Surgical volume–outcome relationships are well established but have not been studied in
patients with interstitial lung disease (ILD) undergoing surgical lung biopsy (SLB). Our study …
patients with interstitial lung disease (ILD) undergoing surgical lung biopsy (SLB). Our study …
Impact of pretreatment interstitial lung disease on radiation pneumonitis and survival in patients treated with lung stereotactic body radiation therapy (SBRT)
Introduction The purpose of this study was to determine the impact of interstitial lung disease
(ILD) on radiation pneumonitis (RP) and overall survival (OS) in lung stereotactic body …
(ILD) on radiation pneumonitis (RP) and overall survival (OS) in lung stereotactic body …
Treatment of gastroesophageal reflux in patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis
Background Gastroesophageal reflux (GER) is common in patients with idiopathic pulmonary
fibrosis (IPF) and has been proposed as a potential contributor to disease progression and …
fibrosis (IPF) and has been proposed as a potential contributor to disease progression and …