User profiles for Shamir R. Mehta
 | Shamir MehtaProfessor of Medicine, McMaster University and Hamilton Health Sciences Verified email at mcmaster.ca Cited by 64899 |
Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study
Background Despite the use of aspirin, there is still a risk of ischaemic events after
percutaneous coronary intervention (PCI). We aimed to find out whether, in addition to aspirin, …
percutaneous coronary intervention (PCI). We aimed to find out whether, in addition to aspirin, …
Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre …
Background Small trials have suggested that radial access for percutaneous coronary
intervention (PCI) reduces vascular complications and bleeding compared with femoral access. …
intervention (PCI) reduces vascular complications and bleeding compared with femoral access. …
[HTML][HTML] Early versus delayed invasive intervention in acute coronary syndromes
SR Mehta, CB Granger, WE Boden… - … England Journal of …, 2009 - Mass Medical Soc
Background Earlier trials have shown that a routine invasive strategy improves outcomes in
patients with acute coronary syndromes without ST-segment elevation. However, the optimal …
patients with acute coronary syndromes without ST-segment elevation. However, the optimal …
Adverse impact of bleeding on prognosis in patients with acute coronary syndromes
Background— The use of multiple antithrombotic drugs and aggressive invasive strategies
has increased the risk of major bleeding in acute coronary syndrome (ACS) patients. It is not …
has increased the risk of major bleeding in acute coronary syndrome (ACS) patients. It is not …
Radial versus femoral access for coronary angiography or intervention and the impact on major bleeding and ischemic events: a systematic review and meta-analysis …
BACKGROUND: Small randomized trials have demonstrated that radial access reduces
access site complications compared to a femoral approach. The objective of this meta-analysis …
access site complications compared to a femoral approach. The objective of this meta-analysis …
Effects of fondaparinux on mortality and reinfarction in patients with acute ST-segment elevation myocardial infarction: the OASIS-6 randomized trial.
Context Despite many therapeutic advances, mortality in patients with acute ST-segment
elevation myocardial infarction (STEMI) remains high. The role of additional antithrombotic …
elevation myocardial infarction (STEMI) remains high. The role of additional antithrombotic …
Routine vs selective invasive strategies in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trials
ContextPatients with unstable angina or non–ST-segment elevation myocardial infarction (NSTEMI)
can be cared for with a routine invasive strategy involving coronary angiography …
can be cared for with a routine invasive strategy involving coronary angiography …
Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute …
Background Clopidogrel and aspirin are the most commonly used antiplatelet therapies for
percutaneous coronary intervention (PCI). We assessed the effect of various clopidogrel and …
percutaneous coronary intervention (PCI). We assessed the effect of various clopidogrel and …
Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable …
Background— We studied the benefits and risks of adding clopidogrel to different doses of
aspirin in the treatment of patients with acute coronary syndrome (ACS). Methods and Results…
aspirin in the treatment of patients with acute coronary syndrome (ACS). Methods and Results…
Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non–ST-elevation acute coronary syndrome: the …
Background— Antiplatelet therapy and antithrombin therapy have been demonstrated to
reduce the risk of cardiac events in patients presenting with acute coronary syndrome, yet all …
reduce the risk of cardiac events in patients presenting with acute coronary syndrome, yet all …