[PDF][PDF] Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts

…, Y Liu, R Martin-Trevino, L Shang, SP McDermott… - Stem cell reports, 2014 - cell.com
Previous studies have suggested that breast cancer stem cells (BCSCs) mediate metastasis,
are resistant to radiation and chemotherapy, and contribute to relapse. Although several …

Comparison of human cord blood engraftment between immunocompromised mouse strains

SP McDermott, K Eppert, ER Lechman… - Blood, The Journal …, 2010 - ashpublications.org
The nonobese diabetic/severe combined immune deficiency (NOD-scid) xenotransplantation
model is the “gold standard” for assaying human hematopoietic stem cell activity. …

The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells

BY Liu, SP McDermott, SS Khwaja… - Proceedings of the …, 2004 - National Acad Sciences
Ectopic activation of the Wnt signaling pathway is highly oncogenic for many human tissues.
Here, we show that ectopic Wnt signaling increases the effective stem cell activity in mouse …

The transfer of touch DNA from hands to glass, fabric and wood

DJ Daly, C Murphy, SD McDermott - Forensic Science International …, 2012 - Elsevier
The transfer of DNA from hands to objects by holding or touching has been examined in the
past. The main purpose of this study was to examine the variation in the amount of DNA …

[PDF][PDF] Targeting breast cancer stem cell state equilibrium through modulation of redox signaling

…, Y Wang, R Harouaka, A Lozier, D Triner, S McDermott… - Cell metabolism, 2018 - cell.com
Although breast cancer stem cells (BCSCs) display plasticity transitioning between quiescent
mesenchymal-like (M) and proliferative epithelial-like (E) states, how this plasticity is …

The use of membrane filters applied directly to the surface of agar plates for the isolation of Campylobacter jejuni from feces

TW Steele, SN McDermott - Pathology, 1984 - Elsevier
Cellulose triacetate membrane filters applied directly to the surface of non-selective blood
agar plates were found to be as effective as the use of antibiotic media in isolating …

[HTML][HTML] Targeting breast cancer stem cells

SP McDermott, MS Wicha - Molecular oncology, 2010 - Elsevier
The cancer stem cell (CSC) hypothesis postulates that tumors are maintained by a self-renewing
CSC population that is also capable of differentiating into non-self-renewing cell …

[HTML][HTML] MicroRNA93 regulates proliferation and differentiation of normal and malignant breast stem cells

…, I Ibarra, R Martin-Trevino, S Bai, SP McDermott… - PLoS …, 2012 - journals.plos.org
MicroRNAs (miRNAs) play important roles in normal cellular differentiation and oncogenesis.
microRNA93 (mir-93), a member of the mir106b-25 cluster, located in intron 13 of the …

Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells

Y Eberhard, SP McDermott, X Wang… - Blood, The Journal …, 2009 - ashpublications.org
Off-patent drugs with previously unrecognized anticancer activity could be rapidly repurposed
for this new indication. To identify such compounds, we conducted 2 independent cell-…

[HTML][HTML] Drosophila perlecan modulates FGF and hedgehog signals to activate neural stem cell division

…, M Johns, M Nayak, CJR Welsh, S McDermott… - Developmental …, 2003 - Elsevier
Mutations in the Drosophila trol gene cause cell cycle arrest of neuroblasts in the larval brain.
Here, we show that trol encodes the Drosophila homolog of Perlecan and regulates …