Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial

…, M Walsh, SW Klarenbach, G Mortis, N Scott-Douglas… - Jama, 2007 - jamanetwork.com
ContextMorbidity and mortality rates in hemodialysis patients remain excessive. Alterations
in the delivery of dialysis may lead to improved patient outcomes.ObjectiveTo compare the …

Associations between acute kidney injury and cardiovascular and renal outcomes after coronary angiography

…, P Faris, N Pannu, BJ Manns, SW Klarenbach… - Circulation, 2011 - Am Heart Assoc
Background— Acute kidney injury (AKI) is associated with early mortality after percutaneous
coronary revascularization procedures, but its prognostic relevance to long-term clinical …

Glomerular filtration rate, proteinuria, and the incidence and consequences of acute kidney injury: a cohort study

…, N Wiebe, N Pannu, BJ Manns, SW Klarenbach… - The Lancet, 2010 - thelancet.com
Background Low values of estimated glomerular filtration rate (eGFR) predispose to acute
kidney injury, and proteinuria is a marker of kidney disease. We aimed to investigate how …

Kidney stones and kidney function loss: a cohort study

…, A Bello, C Morgan, S Samuel, SW Klarenbach… - Bmj, 2012 - bmj.com
Objective To investigate whether the presence of kidney stones increase the risk of end
stage renal disease (ESRD) or other adverse renal outcomes. Design A registry cohort study …

[HTML][HTML] Methods for identifying 30 chronic conditions: application to administrative data

…, BR Hemmelgarn, MT James, SW Klarenbach… - BMC medical informatics …, 2016 - Springer
Background Multimorbidity is common and associated with poor clinical outcomes and high
health care costs. Administrative data are a promising tool for studying the epidemiology of …

[HTML][HTML] Acute kidney injury following coronary angiography is associated with a long-term decline in kidney function

…, P Faris, ML Knudtson, N Pannu, SW Klarenbach… - Kidney international, 2010 - Elsevier
To determine whether acute kidney injury results in later long-term decline in kidney
function we measured changes in kidney function over a 3-year period in adults undergoing …

Economic evaluation of dialysis therapies

SW Klarenbach, M Tonelli, B Chui… - Nature Reviews …, 2014 - nature.com
The prevalence of chronic kidney disease and end-stage renal disease requiring dialysis
therapy continues to increase worldwide, and despite technological advances, treatment …

Comparison of the complexity of patients seen by different medical subspecialists in a universal health care system

…, N Wiebe, BJ Manns, SW Klarenbach… - JAMA network …, 2018 - jamanetwork.com
Importance Clinical experience suggests that there are substantial differences in patient
complexity across medical specialties, but empirical data are lacking. Objective To compare the …

[HTML][HTML] Comorbidity as a driver of adverse outcomes in people with chronic kidney disease

…, MT James, H Quan, M Fortin, SW Klarenbach… - Kidney international, 2015 - Elsevier
Chronic kidney disease (CKD) is associated with poor outcomes, perhaps due to a high
burden of comorbidity. Most studies of CKD populations focus on concordant comorbidities, …

Intensive and standard blood pressure targets in patients with type 2 diabetes mellitus: systematic review and meta-analysis

…, M Tonelli, LA Leiter, SW Klarenbach… - Archives of internal …, 2012 - jamanetwork.com
Background Treatment of hypertension in patients with diabetes mellitus (DM) has been shown
to improve cardiovascular outcomes; however, the value of intensive blood pressure (BP…