In this study, we have aimed at developing a novel electrochemical sensing approach
capable of detecting dopamine, the main biomarker in Parkinson's disease, within the highly …

Biomechanical cues such as shear stress, stretching, compression, and matrix elasticity are
vital in the establishment of next generation physiological in vitro tissue models. Matrix …

Knowledge on the availability of dissolved oxygen inside microfluidic cell culture systems is
vital for recreating physiological-relevant microenvironments and for providing reliable and …

Translation of advanced cell-based assays exhibiting a higher degree of automation,
miniaturization, and integration of complementary sensing functions is mainly limited by the …

Reengineering functional vascular networks in vitro remains an integral part in tissue
engineering, since the incorporation of non-perfused tissues results in restricted nutrient supply …

Rheumatoid arthritis is characterised by a progressive, intermittent inflammation at the
synovial membrane, which ultimately leads to the destruction of the synovial joint. The synovial …

The re-creation of physiological cellular microenvironments that truly resemble complex in
vivo architectures is the key aspect in the development of advanced in vitro organotypic tissue …

Affecting millions of individuals worldwide, neurodegenerative diseases (NDDs) pose a
significant and growing health concern in people over the age of 60 years. Contributing to this …

The understanding that systemic context and tissue crosstalk are essential keys for bridging
the gap between in vitro models and in vivo conditions led to a growing effort in the last …

Organ-on-a-chip technology has the potential to accelerate pharmaceutical drug development,
improve the clinical translation of basic research, and provide personalized intervention …