Background There is much controversy about the use of computed tomography (CT) for
patients with minor head injury. We aimed to develop a highly sensitive clinical decision rule for …

ContextHigh levels of variation and inefficiency exist in current clinical practice regarding
use of cervical spine (C-spine) radiography in alert and stable trauma patients.ObjectiveTo …

Objective: To assess the feasibility and impact of introducing the Ottawa ankle rules to a
large number of physicians in a wide variety of hospital and community settings over a …

There is growing interest in the use of mesenchymal stem cells (MSC) for immune therapy.
Clinical trials that use MSC for treatment of therapy resistant graft versus host disease, …

OBJECTIVE: To simplify airway management and minimize cardiopulmonary resuscitation (CPR)
chest compression interruptions, some emergency medical services (EMS) …

Study objective: To determine the frequency of utilization, yield for brain injury, incidence of
missed injury, and variation in the use of computed tomography (CT) for ED patients with …

Plant-derived flavonoids are inhibitors of various intracellular processes, notably phosphorylation
pathways, and potential inhibitors of cellular autoimmunity. In this study, the inhibiting …

Head injuries are among the most common types of trauma seen in North American
emergency departments, with an estimated 1 million cases seen annually. “Minor” head injury (…

Flavonoids are food components that appear to have potential beneficial health effects. There
is a range of in vitro studies supporting the anti-oxidant and anti-inflammatory properties of …

TLR3 recognizes dsRNAs and is considered of key importance to antiviral host-defense
responses. TLR3 also triggers neuroprotective responses in astrocytes and controls the growth …