Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …

Background Crohn's disease and ulcerative colitis are complex disorders with some shared
and many unique predisposing genes. Accurate phenotype classification is essential in …

Background: The diagnosis of pediatric-onset inflammatory bowel disease (PIBD) can be
challenging in choosing the most informative diagnostic tests and correctly classifying PIBD …

Children and adolescents with Crohn's disease (CD) present often with a more complicated
disease course compared to adult patients. In addition, the potential impact of CD on growth, …

Background & Aims: Childhood-onset inflammatory bowel disease (IBD) might be etiologically
different from adult-onset IBD. We analyzed disease phenotypes and progression of …

Objective We aimed to provide an evidence-supported update of the ECCO-ESPGHAN
guideline on the medical management of paediatric Crohn’s disease [CD]. Methods We formed …

Background Anti-TNF drugs are effective treatments for the management of Crohn's disease
but treatment failure is common. We aimed to identify clinical and pharmacokinetic factors …

The inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis are common
causes of morbidity in children and young adults in the western world. Here we report the …

Methods: A group of 27 experts in pediatric IBD participated in an iterative consensus
process including 2 face-to-face meetings, following an open call to ESPGHAN and ECCO …

Background: The contemporary management of ambulatory ulcerative colitis (UC) continues
to be challenging with∼ 20% of children needing a colectomy within childhood years. We …