Five steps to conducting a systematic review
KS Khan, R Kunz, J Kleijnen… - Journal of the royal …, 2003 - journals.sagepub.com
Systematic reviews and meta-analyses are a key element of evidence-based healthcare, yet
they remain in some ways mysterious. Why did the authors select certain studies and reject …
they remain in some ways mysterious. Why did the authors select certain studies and reject …
GRADE guidelines: 3. Rating the quality of evidence
…, HJ Schünemann, AD Oxman, R Kunz… - Journal of clinical …, 2011 - Elsevier
This article introduces the approach of GRADE to rating quality of evidence. GRADE specifies
four categories—high, moderate, low, and very low—that are applied to a body of evidence…
four categories—high, moderate, low, and very low—that are applied to a body of evidence…
What is “quality of evidence” and why is it important to clinicians?
… Regina Kunz, associate professor3, … 5 Department of Epidemiology, CLARITY Research
Group, Italian National Cancer Institute Regina Elena, Rome, Italy … Articles by Regina Kunz …
Group, Italian National Cancer Institute Regina Elena, Rome, Italy … Articles by Regina Kunz …
Going from evidence to recommendations
… Regina Kunz, associate professor3, … 6 Department of Epidemiology, CLARITY Research
Group, Italian National Cancer Institute Regina Elena, Rome, Italy … Articles by Regina Kunz …
Group, Italian National Cancer Institute Regina Elena, Rome, Italy … Articles by Regina Kunz …
GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables
This article is the first of a series providing guidance for use of the Grading of Recommendations
Assessment, Development, and Evaluation (GRADE) system of rating quality of …
Assessment, Development, and Evaluation (GRADE) system of rating quality of …
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Guidelines are inconsistent in how they rate the quality of evidence and the strength of
recommendations. This article explores the advantages of the GRADE system, which is …
recommendations. This article explores the advantages of the GRADE system, which is …
GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)
In the GRADE approach, randomized trials start as high-quality evidence and observational
studies as low-quality evidence, but both can be rated down if most of the relevant evidence …
studies as low-quality evidence, but both can be rated down if most of the relevant evidence …
GRADE guidelines 6. Rating the quality of evidence—imprecision
GRADE suggests that examination of 95% confidence intervals (CIs) provides the optimal
primary approach to decisions regarding imprecision. For practice guidelines, rating down the …
primary approach to decisions regarding imprecision. For practice guidelines, rating down the …
GRADE guidelines: 7. Rating the quality of evidence—inconsistency
This article deals with inconsistency of relative (rather than absolute) treatment effects in
binary/dichotomous outcomes. A body of evidence is not rated up in quality if studies yield …
binary/dichotomous outcomes. A body of evidence is not rated up in quality if studies yield …
Perioperative management of antithrombotic therapy: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based …
…, M Mayr, AK Jaffer, MH Eckman, AS Dunn, R Kunz - Chest, 2012 - Elsevier
Background This guideline addresses the management of patients who are receiving
anticoagulant or antiplatelet therapy and require an elective surgery or procedure. Methods The …
anticoagulant or antiplatelet therapy and require an elective surgery or procedure. Methods The …