Surgical site infections

PY Young, RG Khadaroo - Surgical Clinics, 2014 - surgical.theclinics.com
Surgical site infections (SSIs) have played a major role in the evolution of medical care
throughout history. Wound complications contributed significantly to the historical surgical …

Comprehensive geriatric assessment for older people admitted to a surgical service

…, T Chambers, X Shi, RG Khadaroo - Cochrane Database …, 2018 - cochranelibrary.com
Background Aging populations are at increased risk of postoperative complications. New
methods to provide care for older people recovering from surgery may reduce surgery‐related …

Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages

KA Powers, K Szászi, RG Khadaroo… - The Journal of …, 2006 - rupress.org
Oxidative stress generated by ischemia/reperfusion is known to prime inflammatory cells for
increased responsiveness to subsequent stimuli, such as lipopolysaccharide (LPS). The …

Sarcopenia is a predictor of outcomes in very elderly patients undergoing emergency surgery

…, CJ Karvellas, V Baracos, DC Williams, RG Khadaroo… - Surgery, 2014 - Elsevier
Background With the increasing aging population, the number of very elderly patients (age
≥80 years) undergoing emergency operations is increasing. Evaluating patient-specific risk …

Soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: suppressing T cell proliferation and inhibiting maturation of bone marrow-derived …

CWY Chan, LS Kay, RG Khadaroo… - The Journal of …, 2003 - journals.aai.org
Fibrinogen-like protein 2 (fgl2)/fibroleukin is a member of the fibrinogen-related protein
superfamily. In addition to its established role in triggering thrombosis, it is known to be secreted …

Management of sarcopenia: a network meta-analysis of randomized controlled trials

…, J Lee, R Hamidian, CA Jones, RG Khadaroo - Journal of the American …, 2022 - Elsevier
Objective This study aimed to determine the comparative effectiveness of interventions in
treatment of sarcopenia. The primary outcome was the measure of treatment effect on muscle …

[HTML][HTML] Measuring resource utilization: a systematic review of validated self-reported questionnaires

LE Leggett, RG Khadaroo, J Holroyd-Leduc… - Medicine, 2016 - journals.lww.com
A variety of methods may be used to obtain costing data. Although administrative data are
most commonly used, the data available in these datasets are often limited. An alternative …

[HTML][HTML] Review of risk assessment tools to predict morbidity and mortality in elderly surgical patients

…, DB Rolfson, LM Warkentin, RG Khadaroo - The American Journal of …, 2018 - Elsevier
Background Informed surgical consent requires accurate estimation of risks and benefits.
Multiple risk assessment tools are available; however, most are not widely used or are specific …

[HTML][HTML] Predictors of in-hospital mortality and complications in very elderly patients undergoing emergency surgery

…, D Hudson, SL Widder, RG Khadaroo - World Journal of …, 2014 - Springer
Introduction With the increasing aging population demographics and life expectancies the
number of very elderly patients (age ≥ 80) undergoing emergency surgery is expected to rise. …

[HTML][HTML] Perioperative factors predicting poor outcome in elderly patients following emergency general surgery: a multivariate regression analysis

…, S Merani, K Tauh, RG Khadaroo - Canadian journal of …, 2015 - ncbi.nlm.nih.gov
Background Older adults (≥ 65 yr) are the fastest growing population and are presenting in
increasing numbers for acute surgical care. Emergency surgery is frequently life threatening …