[HTML][HTML] Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection
…, X Gao, YY Kong, RM Gorczynski… - The Journal of …, 2000 - Am Soc Clin Investig
Periodontitis, a prime cause of tooth loss in humans, is implicated in the increased risk of
systemic diseases such as heart failure, stroke, and bacterial pneumonia. The mechanisms by …
systemic diseases such as heart failure, stroke, and bacterial pneumonia. The mechanisms by …
The relationship of interleukin-1 and immune functions to sleep in humans.
…, J Eisen, E Keystone, RM Gorczynski - Psychosomatic …, 1986 - journals.lww.com
: Serial sampling of peripheral blood from six healthy adult male volunteers was performed
during daytime waking and nighttime sleeping. In addition, sleep physiology was assessed in …
during daytime waking and nighttime sleeping. In addition, sleep physiology was assessed in …
[HTML][HTML] The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis
…, MWC Chan, W He, RM Gorczynski… - The Journal of …, 2003 - Am Soc Clin Investig
Fibrin deposition and thrombosis within the microvasculature is now appreciated to play a
pivotal role in the hepatocellular injury observed in experimental and human viral hepatitis. …
pivotal role in the hepatocellular injury observed in experimental and human viral hepatitis. …
An immunoadhesin incorporating the molecule OX-2 is a potent immunosuppressant that prolongs allo-and xenograft survival
RM Gorczynski, MS Cattral, Z Chen, J Hu… - The Journal of …, 1999 - journals.aai.org
We have established that, in mice receiving donor-specific immunization by the portal vein,
the increased graft survival seen is associated with the increased expression of a molecule (…
the increased graft survival seen is associated with the increased expression of a molecule (…
Soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: suppressing T cell proliferation and inhibiting maturation of bone marrow-derived …
…, KJ Young, LI Zhang, RM Gorczynski… - The Journal of …, 2003 - journals.aai.org
Fibrinogen-like protein 2 (fgl2)/fibroleukin is a member of the fibrinogen-related protein
superfamily. In addition to its established role in triggering thrombosis, it is known to be secreted …
superfamily. In addition to its established role in triggering thrombosis, it is known to be secreted …
Augmented induction of CD4+ CD25+ Treg using monoclonal antibodies to CD200R
RM Gorczynski, L Lee, I Boudakov - Transplantation, 2005 - journals.lww.com
Background. CD200 is a transmembrane protein delivering immunoregulatory signals after
engagement of CD200R. A family of CD200Rs exist (CD200R1–4) with different tissue …
engagement of CD200R. A family of CD200Rs exist (CD200R1–4) with different tissue …
CD200 immunoadhesin suppresses collagen-induced arthritis in mice
RM Gorczynski, Z Chen, K Yu, J Hu - Clinical immunology, 2001 - Elsevier
DBA/1 mice immunized with 100 μg bovine collagen type II emulsified in Freund's adjuvant,
followed by booster injection in incomplete adjuvant at 18 days, develop profound arthritis (>…
followed by booster injection in incomplete adjuvant at 18 days, develop profound arthritis (>…
CD200 and its receptors as targets for immunoregulation.
RM Gorczynski - Current opinion in investigational drugs (London …, 2005 - europepmc.org
A diverse array of cell surface receptors is known to control immune function, reflecting the
integration of positive and negative signaling. Many receptors with opposing functions are …
integration of positive and negative signaling. Many receptors with opposing functions are …
The FGL2‐FcγRIIB pathway: A novel mechanism leading to immunosuppression
…, DA Clark, DE Isenman, RM Gorczynski… - European journal of …, 2008 - Wiley Online Library
Fibrinogen‐like protein 2 (FGL2) is a multifunctional protein, which has been implicated in
the pathogenesis of allograft and xenograft rejection. Previously, FGL2 was shown to inhibit …
the pathogenesis of allograft and xenograft rejection. Previously, FGL2 was shown to inhibit …
Sleep-deprived mice show altered cytokine production manifest by perturbations in serum IL-1ra, TNFa, and IL-6 levels
J Hu, Z Chen, CP Gorczynski, LY Gorczynski… - Brain, behavior, and …, 2003 - Elsevier
Serum cytokine and chemokine levels were examined in mice following 36h of sleep deprivation,
or after exposure to a known physical stressor (rotational stress). Significant changes …
or after exposure to a known physical stressor (rotational stress). Significant changes …