Characterization of a mouse model of chronic uremia

RF Gagnon, B Gallimore - Urological research, 1988 - Springer
A mouse model of renal failure, which is induced by the sequential electrocoagulation of the
right renal cortex and left nephrectomy, was examined for the capacity to reproduce the …

A reproducible model for chronic renal failure in the mouse

RF Gagnon, WP Duguid - Urological research, 1983 - Springer
Chronic renal failure was induced in mice using bilateral electrocoagulation of the renal
cortex. Thermal injury via an angled point cautery was applied to the fully exteriorized right …

Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure

N Eliopoulos, RF Gagnon, M Francois… - Journal of the …, 2006 - journals.lww.com
The goal of this research was to develop a strategy to couple stem cell and gene therapy for
in vivo delivery of erythropoietin (Epo) for treatment of anemia of ESRD. It was shown …

Anti-erythropoietin antibody-mediated pure red cell aplasia after treatment with recombinant erythropoietin products: recommendations for minimization of risk

…, R Delage, DL Forrest, RF Gagnon… - Journal of the …, 2004 - journals.lww.com
Since 1998, there has been a marked increase in incidence of pure red cell aplasia
secondary to development of anti-erythropoietin antibodies (Ab+ PRCA) in patients who have …

Natural History of Chronic Staphylococcus epidermidis Foreign Body Infection in a Mouse Model

B Gallimore, RF Gagnon, R Subang… - Journal of Infectious …, 1991 - academic.oup.com
The development and characterization of a mouse model of chronic Staphylococcus
epidermidis foreign body infection was done with two clinical isolates that differed in degree …

Prospective study of urinalysis abnormalities in HIV-positive individuals treated with indinavir

RF Gagnon, SN Tecimer, AK Watters… - American journal of kidney …, 2000 - Elsevier
Indinavir is a potent protease inhibitor widely used in combination with reverse-transcriptase
inhibitors to treat human immunodeficiency virus (HIV) disease. Individuals treated with …

Mesenchymal stromal cells genetically engineered to overexpress IGF-I enhance cell-based gene therapy of renal failure-induced anemia

…, DL Coutu, LE Chalifour, RF Gagnon… - American Journal …, 2008 - journals.physiology.org
We previously demonstrated that erythropoietin (EPO)-secreting mesenchymal stromal cells
(MSC) can be used for the long-term correction of renal failure-induced anemia. The present …

Time-kill efficacy of antibiotics in combination with rifampin against Staphylococcus epidermidis biofilms.

RF Gagnon, GK Richards… - Advances in Peritoneal …, 1994 - europepmc.org
Infections associated with implants are frequently resistant to conventional antibiotic therapy.
This resistance has been ascribed to the presence of bacteria on the artificial surface within …

Subtherapeutic erythropoietin and insulin-like growth factor-1 correct the anemia of chronic renal failure in the mouse

AG Brox, F Zhang, H Guyda, RF Gagnon - Kidney international, 1996 - Elsevier
GAGNON RF, DUGUID WP: A reproducible model of chronic renal failure in the mouse. Urol
GAGNON RF, ANSARI M: Development and progression of uremic changes in the mouse …

ERYTHROCYTOSIS AFTER RENAL TRANSPLANTATION REPRESENTS AN ABNORMALITY OF INSULIN-LIKE GROWTH FACTOR-I AND ITS BINDING PROTEINS1

…, JA Hanley, GS Louis, S Mongrain, RF Gagnon - …, 1998 - journals.lww.com
Background. Secondary erythrocytosis is classically defined by an increase in erythropoietin
(EPO) production. Despite increased levels of EPO often seen in secondary erythrocytosis, …