Many women do not receive folic acid supplements before conception. In response, most of
Canada's cereal grain products were being fortified with folic acid by January, 1998, thereby …

Background: Low maternal vitamin B 12 status may be a risk factor for neural tube defects (NTDs).
Prior studies used relatively insensitive measures of B 12, did not adjust for folate …

OBJECTIVE: Maternal obesity is likely a risk factor for neural tube defects (NTDs). By late
1997, it became mandatory in Canada that all refined wheat flour be fortified with folic acid. …

OBJECTIVE: The purpose of this study was to investigate age-specific spontaneous fetal
loss rates of pregnancies without known chromosomal or structural abnormalities from mid-…

Deletions at 2p16.3 involving exons of NRXN1 are associated with susceptibility for autism
and schizophrenia, and similar deletions have been identified in individuals with …

By January 1998, most of Canada's cereal grain products were being fortified with folic acid.
Among 336,963 women who underwent antenatal maternal serum screening, the …

The TRIO gene encodes a rho guanine exchange factor, the function of which is to exchange
GDP to GTP, and hence to activate Rho GTPases, and has been described to impact …

Background: Maternal body mass and the presence of diabetes mellitus are probable risk
factors for neural tube defects (NTDs). The association between maternal ethnicity and the risk …

OBJECTIVE To investigate the genetic and obstetric implications of false positive Down
syndrome serum screening results. METHODS The study population comprised 162,774 women …

Background Maternal obesity and pre-pregnancy diabetes mellitus, features of the metabolic
syndrome (MetSyn), are individual risk factors for neural tube defects (NTD). Whether they, …