Medulloblastoma (MB) is the most common malignant brain tumor of children. To identify the
genetic alterations in this tumor type, we searched for copy number alterations using high-…

Purpose: GEP-NENs are rare malignancies with increasing incidence. Their molecular
characteristics are still undefined. We explored the underlying biology of GEP-NENs and the …

Signet ring cell carcinoma (SRCC) is rare: about 10% of gastric cancer (GC) and 1% of
colorectal cancer (CRC). SRCC is associated with poor prognosis, however the underlying …

Purpose: The natural history and prognosis of appendiceal adenocarcinomas differ from
those of adenocarcinomas arising in other large bowel sites. We aimed to compare the …

Purpose: NRG/RTOG 0848 was designed to determine whether adjuvant radiation with
fluoropyrimidine sensitization improved survival following gemcitabine-based adjuvant …

… ARID1A mutant samples had higher PD-L1 expression level (P < 0.001), as well as more
estimated infiltrating cytotoxic T lymphocytes (CTLs) (P < 0.001) and monocyte lineage cells (P …

We report the first successful technology integration of chiplets on an active silicon
interposer, fully processed, packaged and tested. Benefits of chiplet-based architectures are …

BACKGROUND In 1982, the Fourth International Workshop on Chromosomes in Leukemia
reviewed data prospectively collected on 716 patients with acute myeloid leukemia (AML) …

Background Scaling up shorter regimens for tuberculosis (TB) prevention such as once
weekly isoniazid–rifapentine (3HP) taken for 3 months is a key priority for achieving targets set …

Lymph nodes (LNs) and distant metastases can arise from independent subclones of the
primary tumor. Herein, we characterized the molecular landscape and the differences between …