BACKGROUND: A preliminary report in six patients suggested that deep brain stimulation (DBS)
of the subcallosal cingulate gyrus (SCG) may provide benefit in treatment-resistant …

Background Treatment-resistant major depressive disorder is common; repetitive transcranial
magnetic stimulation (rTMS) by use of high-frequency (10 Hz) left-side dorsolateral …

Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT) conducted
a revision of the 2009 guidelines by updating the evidence and recommendations. The …

Objective: A prevalence of at least 30% for treatment-resistant depression has prompted the
investigation of alternative treatment strategies. Deep brain stimulation (DBS) is a promising …

Object Deep brain stimulation (DBS) has been recently investigated as a treatment for major
depression. One of the proposed targets for this application is the subcallosal cingulate …

Background Depression is a heterogeneous mental illness. Neurostimulation treatments, by
targeting specific nodes within the brain’s emotion-regulation network, may be useful both …

Background Anorexia nervosa is characterised by a chronic course that is refractory to
treatment in many patients and has one of the highest mortality rates of any psychiatric disorder. …

Background: Deep brain stimulation (DBS) is used to modulate the activity of dysfunctional
brain circuits. The safety and efficacy of DBS in dementia is unknown. Objective: To assess …

Background Conventional rTMS protocols for major depression commonly employ
stimulation sessions lasting >30 min. However, recent studies have sought to improve costs, …

Despite its high toll on society, there has been little recent improvement in treatment efficacy
for major depressive disorder (MDD). The identification of biological markers of successful …