User profiles for Paul Karanicolas

Paul Karanicolas

University of Toronto
Verified email at sunnybrook.ca
Cited by 12273

Prevention of VTE in nonorthopedic surgical patients: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians Evidence-Based …

MK Gould, DA Garcia, SM Wren, PJ Karanicolas… - Chest, 2012 - Elsevier
Background VTE is a common cause of preventable death in surgical patients. Methods We
developed recommendations for thromboprophylaxis in nonorthopedic surgical patients by …

Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression …

M Briel, I Ferreira-Gonzalez, JJ You, PJ Karanicolas… - Bmj, 2009 - bmj.com
Objective To investigate the association between treatment induced change in high density
lipoprotein cholesterol and total death, coronary heart disease death, and coronary heart …

GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles—continuous outcomes

…, TA Furukawa, BC Johnston, P Karanicolas… - Journal of clinical …, 2013 - Elsevier
Presenting continuous outcomes in Summary of Findings tables presents particular challenges
to interpretation. When each study uses the same outcome measure, and the units of that …

[HTML][HTML] Blinding: who, what, when, why, how?

PJ Karanicolas, F Farrokhyar… - Canadian journal of …, 2010 - ncbi.nlm.nih.gov
Blinding refers to the concealment of group allocation from one or more individuals involved
in a clinical research study, most commonly a randomized controlled trial (RCT). Although …

Oxygen therapy for acutely ill medical patients: a clinical practice guideline

…, W Alhazzani, PM Soccal, PJ Karanicolas… - Bmj, 2018 - bmj.com
Applies to: Patients with acute stroke or myocardial infarction 1 00 99 98 97 96 95 94 93 92
91 90 89 88 87 Recommendation 1 Stop oxygen therapy no higher than 96% saturation …

Randomized controlled trials of surgical interventions

F Farrokhyar, PJ Karanicolas, A Thoma… - Annals of …, 2010 - journals.lww.com
Methods: We systematically reviewed the significance of randomized controlled trials in the
evaluation of surgical interventions, discussed the methodological challenges encountered …

The impact of prophylactic dexamethasone on nausea and vomiting after laparoscopic cholecystectomy: a systematic review and meta-analysis

PJ Karanicolas, SE Smith, B Kanbur, E Davies… - Annals of …, 2008 - journals.lww.com
Objective: To determine the impact of prophylactic corticosteroid administration on
postoperative nausea, vomiting, pain and complications in patients undergoing laparoscopic …

Clinical outcomes of robotic surgery compared to conventional surgical approaches (laparoscopic or open): a systematic overview of reviews

…, A Nathens, TA Stukel, PJ Karanicolas - Annals of …, 2021 - journals.lww.com
Objective: Describe clinical outcomes (eg, postoperative complications, survival) after robotic
surgery compared to open or laparoscopic surgery. Background: Robotic surgery utilization …

Metformin in women with type 2 diabetes in pregnancy (MiTy): a multicentre, international, randomised, placebo-controlled trial

…, D Simmons, JFR Barrett, PJ Karanicolas… - The Lancet Diabetes & …, 2020 - thelancet.com
Background Although metformin is increasingly being used in women with type 2 diabetes
during pregnancy, little data exist on the benefits and harms of metformin use on pregnancy …

Quality of life after gastrectomy for adenocarcinoma: a prospective cohort study

PJ Karanicolas, D Graham, M Gönen, VE Strong… - Annals of …, 2013 - journals.lww.com
Background: Gastrectomy remains a major operation with potential for significant deterioration
in patients' health-related quality of life (QOL). This study assessed differences in QOL …